SCHEMBL820676

SCHEMBL820676

CC=[Zr](Cl)CC(C1C=Cc2ccccc21)C1C=Cc2ccccc21

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 1/20 0.34
HTR2A P28223 1/20 0.31
SIGMAR1 Q99720 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6904136 0.83 HTR6 (0.38) HTR6HTR2ASIGMAR1
SCHEMBL617432 0.77 HTR6 (0.30) HTR6HTR2A
SCHEMBL1921591 0.74 HTR2A (0.38) HTR6HTR2ASIGMAR1
SCHEMBL8677603 0.73 HTR6 (0.33) HTR6HTR2ASIGMAR1
SCHEMBL9860034 0.73 HTR2A (0.37) HTR6HTR2ASIGMAR1
SCHEMBL8380397 0.72 HTR6 (0.32) HTR6HTR2ASIGMAR1
SCHEMBL6673086 0.71 HTR2A (0.36) HTR6HTR2ASIGMAR1
SCHEMBL8384531 0.71 HTR2A (0.36) HTR6HTR2ASIGMAR1
SCHEMBL820680 0.71 HTR2A (0.33) HTR6HTR2A
SCHEMBL3383301 0.71 HTR2A (0.38) HTR6HTR2ASIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3480258-B1 SOLID MAO COMPOSITION CONTAINING AL2O3 AND METHOD FOR PRODUCING SAME TOSOH FINECHEM CORP (JP) 2023-12-20 EP disclosed
US-20230137384-A1 ARTICLE OF MANUFACTURE COMPRISING LOCAL ANESTHETIC, BUFFER, AND GLYCOSAMINOGLYCAN IN SYRINGE WITH IMPROVED STABILITY URIGEN PHARMACEUTICALS, INC. 2023-05-04 US disclosed
US-20210283172-A1 ARTICLE OF MANUFACTURE COMPRISING LOCAL ANESTHETIC, BUFFER, AND GLYCOSAMINOGLYCAN IN SYRINGE WITH IMPROVED STABILITY URIGEN PHARMACEUTICALS, INC. 2021-09-16 US disclosed
US-10730969-B2 Solid MAO composition containing Al2O3 and method for producing same TOSOH FINECHEM CORPORATION (JP) 2020-08-04 US disclosed
EP-3318544-B1 PROCESS FOR THE PREPARATION OF POLYMERIZED POLYETHYLENE WAX SCG CHEMICALS CO LTD (TH) 2020-03-18 EP disclosed
EP-3609483-A1 ARTICLE OF MANUFACTURE COMPRISING LOCAL ANESTHETIC, BUFFER, AND GLYCOSAMINOGLYCAN IN SYRINGE WITH IMPROVED STABILITY Urigen Pharmaceuticals, Inc. (US) 2020-02-19 EP disclosed
US-20190263947-A1 PROCESS FOR THE PREPARATION OF POLYMERIZED POLYETHYLENE WAX SCG CHEMICALS CO., LTD. (TH) 2019-08-29 US disclosed
WO-2018191412-A9 ARTICLE OF MANUFACTURE COMPRISING LOCAL ANESTHETIC, BUFFER, AND GLYCOSAMINOGLYCAN IN SYRINGE WITH IMPROVED STABILITY URIGEN PHARMACEUTICALS, INC. (US) 2019-05-31 WO disclosed
EP-3480258-A1 SOLID MAO COMPOSITION CONTAINING AL2O3 AND METHOD FOR PRODUCING SAME Tosoh Finechem Corporation (JP) 2019-05-08 EP disclosed
US-20180355077-A1 SOLID MAO COMPOSITION CONTAINING AL2O3 AND METHOD FOR PRODUCING SAME TOSOH FINECHEM CORPORATION (JP) 2018-12-13 US disclosed
EP-0327649-A1 CATALYST FOR OLEFIN POLYMERIZATION AND PROCESS FOR ITS PREPARATION MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1989-08-16 EP disclosed
EP-0328348-A2 Olefin polymerization catalyst and process for the polymerization of olefins MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1989-08-16 EP disclosed
EP-0324856-A1 PROCESS FOR POLYMERIZING OLEFIN MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1989-07-26 EP disclosed
EP-0314797-A1 OLEFIN POLYMERIZATION CATALYST AND PROCESS FOR POLYMERIZING OLEFIN MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1989-05-10 EP disclosed
EP-0295312-A1 SOLID CATALYST FOR OLEFIN POLYMERIZATION AND PROCESS FOR ITS PREPARATION MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1988-12-21 EP disclosed
EP-0294942-A1 Solid catalyst for polymerizing an olefin MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1988-12-14 EP disclosed
EP-0287666-A1 PROCESS FOR POLYMERIZING OLEFINS Mitsui Chemicals, Inc. (JP) 1988-10-26 EP disclosed
EP-0283164-A2 Cyclo-olefinic random copolymer, olefinic random copolymer, and process for producing cyclo-olefinic random copolymers MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1988-09-21 EP disclosed
EP-0279863-A1 CATALYST FOR POLYMERIZING ALPHA-OLEFIN AND POLYMERIZATION PROCESS MITSUI CHEMICALS, INC. (JP) 1988-08-31 EP disclosed
EP-0279586-A2 Finely divided aluminoxane, process for producing same and its use MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1988-08-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210283172-A1 ARTICLE OF MANUFACTURE COMPRISING LOCAL ANESTHETIC, BUFFER, AND GLYCOSAMINOGLYCAN IN SYRINGE WITH IMPROVED STABILITY OGFR, ALOX5, PTGS1 HTR6 2080/4885HTR2A 2553/4885SIGMAR1 151/4885
US-20230137384-A1 ARTICLE OF MANUFACTURE COMPRISING LOCAL ANESTHETIC, BUFFER, AND GLYCOSAMINOGLYCAN IN SYRINGE WITH IMPROVED STABILITY OGFR, ALOX5, PTGS1 HTR6 2080/4885HTR2A 2553/4885SIGMAR1 151/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.