Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 7/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | NSD2 | O96028 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8199058 | 0.87 | THRB (0.52) | CYP2C19ALOX15LMNAHSD17B10KMT2A | |
| SCHEMBL8211556 | 0.87 | ALOX15 (0.53) | ALOX15LMNAHSD17B10KMT2AMEN1 | |
| SCHEMBL8210407 | 0.83 | KMT2A (0.53) | CYP3A4CYP2C9CYP2C19ALOX15LMNA | |
| SCHEMBL8210426 | 0.82 | ACKR3 (0.53) | CYP3A4ALOX15LMNAHSD17B10KMT2A | |
| SCHEMBL8200539 | 0.81 | HSP90AA1 (0.55) | CYP3A4CYP2C19LMNAKMT2ANSD2 | |
| SCHEMBL8200561 | 0.80 | TAAR1 (0.59) | CYP3A4CYP2C9CYP2C19ALOX15LMNA | |
| SCHEMBL20915155 | 0.80 | GAA (0.72) | ALOX15HSD17B10KMT2ANSD2GAA | |
| SCHEMBL8207225 | 0.79 | HPGD (0.60) | ALOX15LMNAHSD17B10KMT2AMAPK1 | |
| SCHEMBL7425279 | 0.78 | NCEH1 (0.46) | CYP2C19ALOX15LMNAHSD17B10KMT2A | |
| SCHEMBL8206426 | 0.78 | GAA (0.53) | ALOX15LMNAHSD17B10KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143777-A | ENZYME INHIBITORS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-11-07 | — | — | US | disclosed |