Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 17/20 | 0.50 |
| ▸ | FNTB | P49356 | 17/20 | 0.50 |
| ▸ | PGGT1B | P53609 | 4/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8199506 | 1.00 | FNTA (0.50) | FNTAFNTBPGGT1BCA2CA1 | |
| SCHEMBL8198280 | 0.85 | FNTA (0.46) | FNTAFNTBPGGT1BCA2CA1 | |
| SCHEMBL8206389 | 0.85 | FNTA (0.46) | FNTAFNTBPGGT1BCA2CA1 | |
| SCHEMBL8207053 | 0.82 | FNTA (0.52) | FNTAFNTBPGGT1BGPR132 | |
| SCHEMBL8212291 | 0.81 | MRGPRX4 (0.40) | — | |
| SCHEMBL8205624 | 0.80 | CA2 (0.46) | FNTAFNTBPGGT1BCA2CA1 | |
| SCHEMBL8199051 | 0.80 | MRGPRX4 (0.43) | — | |
| SCHEMBL8209147 | 0.79 | FNTA (0.40) | FNTAFNTBPGGT1BCA2CA1 | |
| SCHEMBL8211056 | 0.78 | FNTA (0.40) | FNTAFNTBPGGT1BGPR132 | |
| SCHEMBL8199776 | 0.75 | FNTA (0.49) | FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0975603-A1 | INHIBITORS OF FARNESYL PROTEIN TRANSFERASE | ZENECA LIMITED (GB) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998032741-A1 | INHIBITORS OF FARNESYL PROTEIN TRANSFERASE | ZENECA LIMITED (GB) | 1998-07-30 | — | — | WO | disclosed |