Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 17/20 | 0.52 |
| ▸ | FNTB | P49356 | 17/20 | 0.52 |
| ▸ | PGGT1B | P53609 | 4/20 | 0.51 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.42 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8207294 | 0.82 | FNTA (0.50) | FNTAFNTBPGGT1BGPR132 | |
| SCHEMBL8199506 | 0.82 | FNTA (0.50) | FNTAFNTBPGGT1BGPR132 | |
| SCHEMBL7705994 | 0.81 | AGTR2 (0.54) | FNTAFNTBPGGT1BAGTR2 | |
| SCHEMBL8206389 | 0.79 | FNTA (0.46) | FNTAFNTBPGGT1BUSP2ALDH1A1 | |
| SCHEMBL8198280 | 0.79 | FNTA (0.46) | FNTAFNTBPGGT1BUSP2ALDH1A1 | |
| SCHEMBL8212007 | 0.74 | FNTA (0.49) | FNTAFNTB | |
| SCHEMBL8205624 | 0.74 | CA2 (0.46) | FNTAFNTBPGGT1BUSP2ALDH1A1 | |
| SCHEMBL15601947 | 0.73 | FNTA (0.66) | FNTAFNTBPGGT1BUSP2ALDH1A1 | |
| SCHEMBL8209147 | 0.73 | FNTA (0.40) | FNTAFNTBPGGT1B | |
| SCHEMBL9064439 | 0.72 | FNTA (0.67) | FNTAFNTBPGGT1BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0975603-A1 | INHIBITORS OF FARNESYL PROTEIN TRANSFERASE | ZENECA LIMITED (GB) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998032741-A1 | INHIBITORS OF FARNESYL PROTEIN TRANSFERASE | ZENECA LIMITED (GB) | 1998-07-30 | — | — | WO | disclosed |