Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7888441 | 0.89 | PTGER4 (0.53) | LMNAEPHX2PPARGKMT2APTGER4 | |
| SCHEMBL8210714 | 0.89 | KDM4E (0.51) | LMNAKDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8206605 | 0.88 | NPC1 (0.48) | CNR2NPC1RAB9AATMLMNA | |
| SCHEMBL8207045 | 0.88 | ALDH1A1 (0.53) | CNR2NPC1RAB9AATMLMNA | |
| SCHEMBL8200517 | 0.85 | SMN1; SMN2 (0.53) | LMNAKDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8209588 | 0.83 | LMNA (0.50) | NPC1RAB9ALMNAKDM4EMEN1 | |
| SCHEMBL8210395 | 0.82 | TDP1 (0.58) | NPC1RAB9AKDM4EMEN1KMT2A | |
| SCHEMBL8210314 | 0.80 | ALDH1A1 (0.48) | LMNAKDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7888341 | 0.79 | NR1H4 (0.50) | NPC1RAB9ALMNAEPHX2KMT2A | |
| SCHEMBL8207961 | 0.79 | MGLL (0.53) | NPC1RAB9ALMNAKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143777-A | ENZYME INHIBITORS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-11-07 | — | — | US | disclosed |