Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 7/20 | 0.56 |
| ▸ | CTSL | P07711 | 6/20 | 0.56 |
| ▸ | CTSK | P43235 | 6/20 | 0.56 |
| ▸ | CTSS | P25774 | 5/20 | 0.56 |
| ▸ | TACR1 | P25103 | 2/20 | 0.51 |
| ▸ | TYR | P14679 | 1/20 | 0.51 |
| ▸ | TGM2 | P21980 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5689118 | 0.95 | TACR1 (0.55) | CTSBCTSLCTSKCTSSTACR1 | |
| SCHEMBL17039822 | 0.95 | TACR1 (0.55) | CTSBCTSLCTSKCTSSTACR1 | |
| SCHEMBL14488100 | 0.95 | TACR1 (0.55) | CTSBCTSLCTSKCTSSTACR1 | |
| SCHEMBL13715882 | 0.87 | CTSL (0.55) | CTSBCTSLCTSKCTSSCASP1 | |
| SCHEMBL11301054 | 0.86 | CASP1 (0.50) | CTSBCTSLCTSKCTSSTACR1 | |
| SCHEMBL10753165 | 0.86 | CTSL (0.51) | CTSBCTSLCTSKCTSSTACR1 | |
| SCHEMBL22657970 | 0.85 | CASP1 (0.60) | CASP1 | |
| SCHEMBL22657972 | 0.85 | CASP1 (0.60) | CASP1 | |
| SCHEMBL356447 | 0.85 | CTSK (0.53) | CTSBCTSLCTSKCTSSCASP1 | |
| SCHEMBL9044348 | 0.85 | ALDH1A1 (0.47) | CTSBCTSLCTSKCTSSTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1037671-A1 | POLYROTAXANES | SCHERING AKTIENGESELLSCHAFT (DE) | 2000-09-27 | — | — | EP | disclosed |
| WO-1999030744-A1 | POLYROTAXANES | SCHERING AKTIENGESELLSCHAFT (DE) | 1999-06-24 | — | — | WO | disclosed |
| EP-0043247-B1 | PEPTIDES FOR USE IN DETERMINING SERUM THYMIC FACTOR | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1984-02-01 | — | — | EP | disclosed |
| US-4404133-A | TYROSINE DERIVATIVES, SERUM THYMIC FACTOR ANALOGS | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1983-09-13 | — | — | US | disclosed |
| EP-0043247-A1 | Peptides for use in determining serum thymic factor | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1982-01-06 | — | — | EP | disclosed |