Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 0.61 |
| ▸ | NPC1 | O15118 | 7/20 | 0.61 |
| ▸ | RAB9A | P51151 | 7/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 8/20 | 0.57 |
| ▸ | HPGD | P15428 | 6/20 | 0.57 |
| ▸ | TP53 | P04637 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.57 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | STAT1 | P42224 | 1/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8211 | 0.83 | SMN1; SMN2 (0.56) | ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL11082015 | 0.81 | ALOX12 (0.77) | ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E | |
| Isoflavone SCHEMBL6290885 | 0.78 | ALDH1A1 (0.66) | ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E | |
| Isoflavone SCHEMBL6542422 | 0.78 | ALDH1A1 (0.66) | ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E | |
| Isoflavone SCHEMBL8028 | 0.78 | ALDH1A1 (0.66) | ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E | |
| Isoflavone SCHEMBL31264756 | 0.78 | ALDH1A1 (0.66) | ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL5275289 | 0.77 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL23278859 | 0.76 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E | |
| 7-Hydroxy Isoflavone SCHEMBL762528 | 0.76 | KDM4E (1.00) | ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL14994916 | 0.76 | ALDH1A1 (0.78) | ALDH1A1SMN1; SMN2NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12252473-B2 | Preparation methods of quinolone compounds and intermediates thereof | Chongqing University of Arts and Sciences (CN) | 2025-03-18 | — | — | US | disclosed |
| US-20240400522-A1 | PREPARATION METHODS OF QUINOLONE COMPOUNDS AND INTERMEDIATES THEREOF | Chongqing University of Arts and Sciences (CN) | 2024-12-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240400522-A1 | PREPARATION METHODS OF QUINOLONE COMPOUNDS AND INTERMEDIATES THEREOF | NQO2, MRPL21, RECQL | ALDH1A1 1217/4885SMN1; SMN2 4049/4885NPC1 1905/4885 |
| US-12252473-B2 | Preparation methods of quinolone compounds and intermediates thereof | NQO2, MRPL21, RECQL | ALDH1A1 1217/4885SMN1; SMN2 4049/4885NPC1 1905/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.