SCHEMBL8211332

SCHEMBL8211332

C1=CC(N(c2ccccc2)c2cc3ccc4cccc5ccc(c2)c3c45)(N(c2ccccc2)c2cc3ccc4cccc5ccc(c2)c3c45)C=CC1c1ccccc1

nearest known ligand 0.32

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
ERBB2 P04626 1/20 0.32
FYN P06241 1/20 0.32
MAOA P21397 1/20 0.32
ACHE P22303 1/20 0.32
AHR P35869 1/20 0.32
ALDH1A1 P00352 1/20 0.31
CYP1A1 P04798 1/20 0.31
CYP3A4 P08684 1/20 0.31
HPGD P15428 1/20 0.31
TSHR P16473 1/20 0.31
CYP1B1 Q16678 1/20 0.31
HSD17B10 Q99714 1/20 0.31
NPC1 O15118 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8209184 0.90 CYP1A2 (0.32) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL2802019 0.86 KDM1A (0.31) CYP1A2MAOACYP3A4
SCHEMBL8209205 0.84
SCHEMBL5148248 0.81 ALDH1A1 (0.35) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL8201869 0.81 ALDH1A1 (0.37) ALDH1A1CYP3A4HPGDTSHRHSD17B10
SCHEMBL8209242 0.80
SCHEMBL9190411 0.78 TSPO (0.31)
SCHEMBL9192026 0.78 MEN1 (0.32) MEN1KMT2AALDH1A1HSD17B10
SCHEMBL6711335 0.77 PKM (0.30)
SCHEMBL710236 0.77 ALDH1A1 (0.33) MEN1KMT2AACHEALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0977288-A2 Electron-injecting layer formed from a dopant layer for organic light-emitting structure EASTMAN KODAK COMPANY (US) 2000-02-02 EP disclosed