SCHEMBL5148248

SCHEMBL5148248

C1=CC(N(c2ccccc2)c2ccc3c(ccc4ccccc43)c2)(N(c2ccccc2)c2ccc3c(ccc4ccccc43)c2)C=CC1c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.35
HSD17B10 Q99714 2/20 0.35
CYP1B1 Q16678 2/20 0.35
HIF1A Q16665 1/20 0.35
HPRT1 P00492 3/20 0.33
CYP2A6 P11509 1/20 0.32
TSHR P16473 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
CYP1A2 P05177 2/20 0.31
CYP1A1 P04798 1/20 0.31
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31
ERBB2 P04626 1/20 0.30
FYN P06241 1/20 0.30
MAOA P21397 1/20 0.30
ACHE P22303 1/20 0.30
AHR P35869 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8209205 0.88
SCHEMBL4521937 0.82 KDM4E (0.30) ALDH1A1HSD17B10CYP1A2HPGD
SCHEMBL21500411 0.82 SIGMAR1 (0.32)
SCHEMBL8211332 0.81 CYP1A2 (0.32) ALDH1A1HSD17B10CYP1B1TSHRCYP1A2
SCHEMBL16331595 0.81 CA12 (0.36) CYP1A2
SCHEMBL419796 0.80 SIGMAR1 (0.38) ALDH1A1CYP1A2
SCHEMBL8209184 0.80 CYP1A2 (0.32) ALDH1A1HSD17B10CYP1A2HPGDERBB2
SCHEMBL6711335 0.78 PKM (0.30)
SCHEMBL8201869 0.76 ALDH1A1 (0.37) ALDH1A1HSD17B10HIF1ATSHRHPGD
SCHEMBL1255774 0.76 CYP2C19 (0.35) ALDH1A1TSHRACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3719546-B1 OPTICAL FILM LG CHEMICAL LTD (KR) 2023-08-16 EP disclosed
CN-111512192-B Optical film 株式会社LG化学 2022-05-17 CN disclosed
EP-3719546-A1 OPTICAL FILM LG CHEM, LTD. (KR) 2020-10-07 EP disclosed
CN-111512192-A Optical film 株式会社LG化学 2020-08-07 CN disclosed
US-8207914-B2 OLED display with aging compensation GLOBAL OLED TECHNOLOGY LLC (US) 2012-06-26 US disclosed
US-20070103411-A1 OLED display with aging compensation EASTMAN KODAK COMPANY 2007-05-10 US disclosed
EP-0977288-A2 Electron-injecting layer formed from a dopant layer for organic light-emitting structure EASTMAN KODAK COMPANY (US) 2000-02-02 EP disclosed