Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 3/20 | 0.61 |
| ▸ | ESR1 | P03372 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.52 |
| ▸ | THRB | P10828 | 2/20 | 0.52 |
| ▸ | RECQL | P46063 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.48 |
| ▸ | TUBB | P07437 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16591527 | 0.91 | ESR2 (0.74) | ESR2ESR1MAPTGAAALDH1A1 | |
| Diphenylamine SCHEMBL8206764 | 0.85 | ESR1 (0.77) | ESR2ESR1MAPTRAB9AMAPK1 | |
| SCHEMBL8212109 | 0.84 | MAPT (0.47) | ESR2MAPTRAB9AMAPK1KDM4E | |
| SCHEMBL9171254 | 0.83 | ESR2 (0.61) | ESR2ESR1MAPTRAB9AMAPK1 | |
| SCHEMBL8207410 | 0.83 | ESR1 (0.67) | ESR2ESR1MAPTRAB9AMAPK1 | |
| SCHEMBL25048 | 0.82 | CA4 (0.56) | ESR2ESR1MAPK1KMT2ALTA4H | |
| SCHEMBL7256133 | 0.82 | MAPT (0.77) | ESR2MAPTRAB9AMAPK1KDM4E | |
| SCHEMBL4570566 | 0.82 | CA4 (0.56) | ESR2ESR1MAPK1KMT2ALTA4H | |
| SCHEMBL465381 | 0.80 | ESR1 (0.58) | ESR2ESR1MAPTRAB9AMAPK1 | |
| SCHEMBL23626098 | 0.79 | ESR2 (0.55) | ESR2ESR1MAPTGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6093784-A | (CO)POLYCARBONATE CONTAINING DIARYLAMINOPHENYL-SUBSTITUTED BISPHENOL UNITS; DURABILITY, HEAT RESISTANCE, RADIATION TRANSPARENCY | RICOH COMPANY, LTD. (JP) | 2000-07-25 | — | — | US | disclosed |