Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.77 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.77 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.45 |
| ▸ | TYR | P14679 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
| ▸ | ESRRG | P62508 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8207410 | 0.90 | ESR1 (0.67) | ESR1ESR2CYP3A4ALDH1A1HSD17B10 | |
| SCHEMBL8031149 | 0.88 | ESR1 (1.00) | ESR1ESR2CYP3A4ALDH1A1TSHR | |
| SCHEMBL27277 | 0.88 | ESR1 (1.00) | ESR1ESR2CYP3A4ALDH1A1TSHR | |
| SCHEMBL465381 | 0.86 | ESR1 (0.58) | ESR1ESR2CYP3A4ALDH1A1TSHR | |
| Methane SCHEMBL16667289 | 0.86 | ESR1 (0.95) | ESR1ESR2CYP3A4ALDH1A1TSHR | |
| Phenol SCHEMBL29851136 | 0.86 | ESR1 (0.95) | ESR1ESR2CYP3A4ALDH1A1TSHR | |
| SCHEMBL8211337 | 0.85 | ESR2 (0.61) | ESR1ESR2CYP3A4ALDH1A1HSD17B10 | |
| Phenol SCHEMBL8987629 | 0.83 | ESR1 (0.91) | ESR1ESR2CYP3A4ALDH1A1TSHR | |
| SCHEMBL23059478 | 0.82 | ESR1 (0.87) | ESR1ESR2CYP3A4ALDH1A1TSHR | |
| Bicarbonate SCHEMBL19723102 | 0.82 | ESR1 (0.87) | ESR1ESR2CYP3A4ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6093784-A | (CO)POLYCARBONATE CONTAINING DIARYLAMINOPHENYL-SUBSTITUTED BISPHENOL UNITS; DURABILITY, HEAT RESISTANCE, RADIATION TRANSPARENCY | RICOH COMPANY, LTD. (JP) | 2000-07-25 | — | — | US | disclosed |
| US-5830980-A | FROM (DIARYLAMINO)BENZYLIDENEDIPHENOLS AND BIS/CHLOROFORMATES | RICOH COMPANY, LTD. (JP) | 1998-11-03 | — | — | US | disclosed |
| US-5747204-A | DURABILITY, PHOTOSENSITIVITY; COPIERS, PRINTERS | RICOH COMPANY, LTD. (JP) | 1998-05-05 | — | — | US | disclosed |