Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7593765 | 0.64 | LMNA (0.40) | LMNACYP2C9CHRM1TBXA2RPDE4A | |
| SCHEMBL29181466 | 0.64 | LMNA (0.50) | LMNACYP2C9CHRM1TBXA2RPDE4A | |
| SCHEMBL8812365 | 0.63 | SMN1; SMN2 (0.38) | LMNASLC6A3 | |
| SCHEMBL9717831 | 0.60 | LMNA (0.42) | LMNACYP2C9CHRM1TBXA2RPDE4A | |
| SCHEMBL22168546 | 0.60 | LMNA (0.37) | LMNACYP2C9CHRM1TBXA2RPDE4A | |
| SCHEMBL11571718 | 0.59 | LMNA (0.53) | LMNACYP2C9CHRM1TBXA2RPDE4A | |
| SCHEMBL10932897 | 0.58 | LMNA (0.43) | LMNACYP2C9CHRM1TBXA2RPDE4A | |
| SCHEMBL8812562 | 0.58 | CA2 (0.50) | LMNA | |
| SCHEMBL11571749 | 0.56 | LMNA (0.35) | LMNACYP2C9CHRM1TBXA2RPDE4A | |
| SCHEMBL9717818 | 0.56 | LMNA (0.50) | LMNACYP2C9CHRM1TBXA2RPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0973553-A2 | BLOOD-POOL CARRIER FOR LIPOPHILIC IMAGING AGENTS | THE BOARD OF REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2000-01-26 | — | — | EP | disclosed |
| WO-1998046275-A2 | BLOOD-POOL CARRIER FOR LIPOPHILIC IMAGING AGENTS | THE BOARD OF REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1998-10-22 | — | — | WO | disclosed |