Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9696073 | 0.72 | LMNA (0.49) | LMNACYP2C9CHRM1TBXA2RPDE4A | |
| SCHEMBL9717764 | 0.68 | LMNA (0.38) | LMNACYP2C9CHRM1TBXA2RPDE4A | |
| SCHEMBL9717761 | 0.67 | LMNA (0.37) | LMNACYP2C9CHRM1TBXA2RPDE4A | |
| SCHEMBL6251797 | 0.66 | TSHR (0.31) | — | |
| SCHEMBL8213482 | 0.64 | LMNA (0.39) | LMNACYP2C9CHRM1TBXA2RPDE4A | |
| SCHEMBL9685057 | 0.63 | TSHR (0.36) | — | |
| SCHEMBL9387753 | 0.63 | CFTR (0.41) | LMNACYP2C9CHRM1TBXA2RPDE4A | |
| SCHEMBL26507122 | 0.62 | MAPT (0.35) | — | |
| SCHEMBL124763 | 0.61 | TSHR (0.46) | LMNACYP2C9CHRM1TBXA2RPDE4A | |
| SCHEMBL6012587 | 0.61 | LMNA (0.40) | LMNACYP2C9CHRM1TBXA2RPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6448442-B1 | X-RAY CONTRAST AGENTS; LOW VISCOSITY IODINATED ARYL COMPOUNDS | AMERSHAM HEALTH AS (NO) | 2002-09-10 | — | — | US | disclosed |
| US-6310243-B1 | BENZENE COMPOUNDS IN WHICH 3 NON-ADJACENT RING ATOMS ARE SUBSTITUTED WITH IODINE, 2 OF THE REMAINING RING ATOMS ARE AMIDE SUBSTITUTED WITH HYDROXY AND THE OTHER REMAINING RING ATOM IS A NON-AMIDE, HYDROXY-SUBSTITUTED NONIONIC MOIETY | NYCOMED IMAGING AS (NO) | 2001-10-30 | — | — | US | disclosed |
| US-5993780-A | A POLYIODOARYLALKYL ALCOHOL OR DERIVATIVE | NYCOMED IMAGING AS (NO) | 1999-11-30 | — | — | US | disclosed |