SCHEMBL821361

SCHEMBL821361

CCCCc1nc(N)nc(-c2ccccc2)n1

nearest known ligand 0.56

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ADORA1 P30542 4/20 0.56
ADORA2A P29274 3/20 0.56
ADORA3 P0DMS8 3/20 0.56
ADORA2B P29275 2/20 0.56
POLB P06746 1/20 0.56
HSP90AA1 P07900 1/20 0.49
HSP90AB1 P08238 1/20 0.49
DHFR P00374 2/20 0.48
NPSR1 Q6W5P4 1/20 0.45
GPR84 Q9NQS5 1/20 0.45
ALOX15 P16050 1/20 0.44
TSHR P16473 1/20 0.44
TLR8 Q9NR97 4/20 0.43
HRH4 Q9H3N8 1/20 0.43
CASP1 P29466 1/20 0.42
ACP1 P24666 1/20 0.41
NR1H3 Q13133 1/20 0.41
HEXA P06865 1/20 0.41
HEXB P07686 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12732279 0.88 GPR84 (0.51) ADORA1ADORA2AADORA3ADORA2BPOLB
SCHEMBL3686148 0.83 ADORA2A (0.64) ADORA1ADORA2AADORA3ADORA2BPOLB
SCHEMBL28827848 0.83 GPR84 (0.58) ADORA1ADORA2AADORA3DHFRGPR84
SCHEMBL28327919 0.81 GPR84 (0.57) ADORA2AADORA3DHFRGPR84ACP1
SCHEMBL1959103 0.80 GPR84 (0.55) ADORA3DHFRGPR84ACP1NR1H3
SCHEMBL4251526 0.80 GPR84 (0.55) ADORA3DHFRGPR84ACP1NR1H3
SCHEMBL19524809 0.77 L3MBTL1 (0.54) ADORA1ADORA2AADORA3ADORA2BPOLB
SCHEMBL27552500 0.77 KDM4E (0.50) ADORA1ADORA2AADORA3ADORA2BPOLB
SCHEMBL808441 0.76 CASP1 (0.71) ADORA1ADORA2AADORA2BTSHRTLR8
SCHEMBL11512959 0.76 CASP1 (0.71) ADORA1ADORA2AADORA2BTSHRTLR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9151883-B2 Cellulose acylate film, retardation film, polarizer and liquid-crystal display device FUJIFILM CORPORATION (JP) 2015-10-06 US disclosed
US-9151883-B2 Cellulose acylate film, retardation film, polarizer and liquid-crystal display device FUJIFILM CORPORATION (JP) 2015-10-06 US disclosed
US-8937696-B2 Cellulose acylate film, its production method, polarizer and liquid crystal display device FUJIFILM CORPORATION (JP) 2015-01-20 US disclosed
US-8937696-B2 Cellulose acylate film, its production method, polarizer and liquid crystal display device FUJIFILM CORPORATION (JP) 2015-01-20 US disclosed
US-8906475-B2 Cellulose acylate film, retardation film, polarizer and liquid-crystal display device FUJIFILM CORPORATION (JP) 2014-12-09 US disclosed
US-8906475-B2 Cellulose acylate film, retardation film, polarizer and liquid-crystal display device FUJIFILM CORPORATION (JP) 2014-12-09 US disclosed
US-20140318413-A1 CELLULOSE ACYLATE FILM, RETARDATION FILM, POLARIZER AND LIQUID-CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2014-10-30 US disclosed
US-20140318413-A1 CELLULOSE ACYLATE FILM, RETARDATION FILM, POLARIZER AND LIQUID-CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2014-10-30 US disclosed
US-8792071-B2 Cellulose acylate film, its production method, polarizer and liquid crystal display device FUJIFILM CORPORATION (JP) 2014-07-29 US disclosed
US-8792071-B2 Cellulose acylate film, its production method, polarizer and liquid crystal display device FUJIFILM CORPORATION (JP) 2014-07-29 US disclosed
US-8158220-B2 Cellulose acylate film, retardation film, polarizer and liquid crystal display device FUJIFILM CORPORATION (JP) 2012-04-17 US disclosed
US-8158220-B2 Cellulose acylate film, retardation film, polarizer and liquid crystal display device FUJIFILM CORPORATION (JP) 2012-04-17 US disclosed
US-20120018685-A1 Optical film, retardation film, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2012-01-26 US disclosed
US-20120018685-A1 Optical film, retardation film, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2012-01-26 US disclosed
US-20110255037-A1 Cellulose acylate film, its production method, polarizer and liquid crystal display device FUJIFILM CORPORATION (JP) 2011-10-20 US disclosed
US-20110255037-A1 Cellulose acylate film, its production method, polarizer and liquid crystal display device FUJIFILM CORPORATION (JP) 2011-10-20 US disclosed
US-20110073007-A1 HUMIDITY DEPENDENCE IMPROVER FOR POLYMER FILM, POLYMER FILM, PROTECTIVE FILM FOR POLARIZER, RETARDATION FILM, POLARIZER, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2011-03-31 US disclosed
US-20110073007-A1 HUMIDITY DEPENDENCE IMPROVER FOR POLYMER FILM, POLYMER FILM, PROTECTIVE FILM FOR POLARIZER, RETARDATION FILM, POLARIZER, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2011-03-31 US disclosed
US-20110076423-A1 CELLULOSE ACYLATE FILM, RETARDATION FILM, POLARIZER AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2011-03-31 US disclosed
US-20110076423-A1 CELLULOSE ACYLATE FILM, RETARDATION FILM, POLARIZER AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2011-03-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110073007-A1 HUMIDITY DEPENDENCE IMPROVER FOR POLYMER FILM, POLYMER FILM, PROTECTIVE FILM FOR POLARIZER, RETARDATION FILM, POLARIZER, AND LIQUID CRYSTAL DISPLAY DEVICE CNKSR1, C1R, PNISR ADORA1 301/4885ADORA2A 640/4885ADORA3 1321/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.