SCHEMBL8215522

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8207992	0.86	KIF11 (0.58)	KIF11EPHX2ALDH1A1PSEN1PSEN2
	SCHEMBL8208199	0.83	TAAR1 (0.56)	ALDH1A1KDM4ERAB9AMEN1HTT
	SCHEMBL8215633	0.76	KIF11 (0.50)	KIF11EPHX2MEN1KMT2AMAPT
	SCHEMBL8216195	0.76	SLC1A3 (0.48)	ALDH1A1RAB9AMAPTNPC1LMNA
	SCHEMBL8215666	0.74	KIF11 (0.48)	KIF11EPHX2PSEN1PSEN2APH1B
	SCHEMBL14494246	0.74	KIF11 (0.48)	KIF11EPHX2PSEN1PSEN2APH1B
	SCHEMBL8212408	0.73	ROCK1 (0.40)	ALDH1A1KDM4ERAB9AMEN1KMT2A
	SCHEMBL11510708	0.73	MLYCD (0.65)	KIF11EPHX2ALDH1A1TRPV1RAB9A
	SCHEMBL134581	0.73	TP53 (0.66)	KIF11EPHX2TRPV1TRPV4MTOR
	SCHEMBL8208217	0.72	SPHK1 (0.47)	RAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.