Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3750086 | 0.86 | KMT2A (0.44) | LMNAADRB2SMN1; SMN2MAPTKMT2A | |
| SCHEMBL3752506 | 0.86 | L3MBTL1 (0.46) | LMNAADRB2SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL3752842 | 0.86 | ALDH1A1 (0.40) | LMNAADRB2SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL3752847 | 0.84 | ALDH1A1 (0.39) | LMNAADRB2SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL3745406 | 0.84 | KDM1A (0.42) | LMNAMAPTNPSR1KMT2AKDM4E | |
| SCHEMBL3752590 | 0.82 | KMO (0.38) | LMNAADRB2SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL3747547 | 0.82 | MEN1 (0.40) | LMNAADRB2SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL3753486 | 0.82 | XDH (0.41) | ALDH1A1MAPTKDM4EHPGDCYP1A2 | |
| SCHEMBL3753774 | 0.81 | RORB (0.40) | KMT2ACYP1A2 | |
| SCHEMBL3751988 | 0.80 | ALDH1A1 (0.37) | LMNAALDH1A1MAPTNPSR1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008031501-A2 | 2-PHENOXY NICOTINE ACID DERIVATIVE AND USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-03-20 | — | — | WO | disclosed |