SCHEMBL10259403

SCHEMBL10259403

CC(=O)n1c(C)nc2cc(C)ccc21

nearest known ligand 0.49

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 4/20 0.44
NPC1 O15118 4/20 0.44
KMT2A Q03164 2/20 0.44
ALDH1A1 P00352 2/20 0.44
HTT P42858 1/20 0.42
HSD17B10 Q99714 2/20 0.40
KDM4E B2RXH2 1/20 0.40
NQO2 P16083 1/20 0.40
ACSS2 Q9NR19 1/20 0.39
POLB P06746 1/20 0.39
MAPT P10636 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
DYRK1A Q13627 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10259406 0.86 KMT2A (0.44) RAB9ANPC1KMT2AALDH1A1NQO2
SCHEMBL822015 0.79 ALDH1A1 (0.68) RAB9ANPC1KMT2AALDH1A1HTT
SCHEMBL17975243 0.79 KMT2A (0.44) RAB9ANPC1KMT2AALDH1A1HTT
SCHEMBL18068779 0.76 ALDH1A1 (0.44) RAB9ANPC1KMT2AALDH1A1HTT
SCHEMBL19911320 0.76 FGFR1 (0.49) RAB9ANPC1KMT2AALDH1A1MAPT
SCHEMBL10980166 0.74 NLRP3 (0.42) RAB9ANPC1KMT2AALDH1A1HTT
SCHEMBL23613732 0.73 P2RX3 (0.43) KMT2AALDH1A1
SCHEMBL6737850 0.73 AGPAT2 (0.41) RAB9ANPC1KMT2AALDH1A1HTT
SCHEMBL1104855 0.72 RAB9A (0.59) RAB9ANPC1KMT2AALDH1A1HTT
SCHEMBL20299801 0.71 MTNR1A (0.48) RAB9ANPC1KMT2AALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8871413-B2 Toners for electrostatic-image development, cartridge employing toner for electrostatic-image development, and image-forming apparatus MITSUBISHI CHEMICAL CORPORATION (JP) 2014-10-28 US disclosed
US-8871413-B2 Toners for electrostatic-image development, cartridge employing toner for electrostatic-image development, and image-forming apparatus MITSUBISHI CHEMICAL CORPORATION (JP) 2014-10-28 US disclosed
US-8404412-B2 Electrophotographic photoreceptor, and image forming apparatus MITSUBISHI CHEMICAL CORPORATION (JP) 2013-03-26 US disclosed
US-8404412-B2 Electrophotographic photoreceptor, and image forming apparatus MITSUBISHI CHEMICAL CORPORATION (JP) 2013-03-26 US disclosed
US-8221950-B2 Image forming apparatus MITSUBISHI CHEMICAL CORPORATION (JP) 2012-07-17 US disclosed
US-8221950-B2 Image forming apparatus MITSUBISHI CHEMICAL CORPORATION (JP) 2012-07-17 US disclosed
US-8211602-B2 Image forming apparatus MITSUBISHI CHEMICAL CORPORATION (JP) 2012-07-03 US disclosed
US-8211602-B2 Image forming apparatus MITSUBISHI CHEMICAL CORPORATION (JP) 2012-07-03 US disclosed
US-8064796-B2 Image forming apparatus MITSUBISHI CHEMICAL CORPORATION (JP) 2011-11-22 US disclosed
US-8064796-B2 Image forming apparatus MITSUBISHI CHEMICAL CORPORATION (JP) 2011-11-22 US disclosed
US-20110038650-A1 TONERS FOR ELECTROSTATIC-IMAGE DEVELOPMENT, CARTRIDGE EMPLOYING TONER FOR ELECTROSTATIC-IMAGE DEVELOPMENT, AND IMAGE-FORMING APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2011-02-17 US disclosed
US-20110038650-A1 TONERS FOR ELECTROSTATIC-IMAGE DEVELOPMENT, CARTRIDGE EMPLOYING TONER FOR ELECTROSTATIC-IMAGE DEVELOPMENT, AND IMAGE-FORMING APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2011-02-17 US disclosed
US-20100316412-A1 IMAGE FORMING APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2010-12-16 US disclosed
US-20100316411-A1 IMAGE FORMING APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2010-12-16 US disclosed
US-20100316411-A1 IMAGE FORMING APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2010-12-16 US disclosed
US-20100316412-A1 IMAGE FORMING APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2010-12-16 US disclosed
US-20100221040-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND APPARATUS FOR IMAGE FORMATION MITSUBISHI CHEMICAL CORPORATION 2010-09-02 US disclosed
US-20100221040-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND APPARATUS FOR IMAGE FORMATION MITSUBISHI CHEMICAL CORPORATION 2010-09-02 US disclosed
US-20090180807-A1 IMAGE FORMING APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2009-07-16 US disclosed
US-20090180807-A1 IMAGE FORMING APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2009-07-16 US disclosed