SCHEMBL822035

SCHEMBL822035

CC1CC(=O)N(c2cccc(N3C(=O)CC(C)C3=O)c2)C1=O

nearest known ligand 0.53

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 10/20 0.49
MEN1 O00255 5/20 0.49
KMT2A Q03164 5/20 0.49
MAPT P10636 4/20 0.49
HTT P42858 1/20 0.49
HSP90AA1 P07900 1/20 0.49
SMN1; SMN2 Q16637 2/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
GAA P10253 1/20 0.46
RAB9A P51151 1/20 0.46
CYP2C19 P33261 1/20 0.44
GFER P55789 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13709052 0.93 L3MBTL1 (0.56) ALDH1A1MEN1KMT2AMAPTHTT
SCHEMBL13884938 0.90 ALDH1A1 (0.62) ALDH1A1MAPTHTTHSP90AA1SMN1; SMN2
SCHEMBL20375597 0.88 MAPT (0.42) ALDH1A1MAPTHTTSMN1; SMN2
SCHEMBL28243691 0.87 ALDH1A1 (0.58) ALDH1A1MAPTSMN1; SMN2GAAGFER
SCHEMBL774049 0.87 ALDH1A1 (0.58) ALDH1A1MAPTSMN1; SMN2GAAGFER
SCHEMBL3485977 0.87 ALDH1A1 (0.58) ALDH1A1MAPTSMN1; SMN2GAAGFER
SCHEMBL13484195 0.85 ALDH1A1 (0.59) ALDH1A1MEN1KMT2AMAPTHTT
SCHEMBL12964166 0.85 LMNA (0.55) ALDH1A1MEN1KMT2AMAPTSMN1; SMN2
SCHEMBL16566170 0.84 ALDH1A1 (0.50) ALDH1A1MAPTHTTHSP90AA1L3MBTL1
SCHEMBL14821834 0.78 ALDH1A1 (0.61) ALDH1A1MEN1KMT2AMAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160208036-A1 SYNTHESIS OF CROSS-LINKED PLANT-OIL BASED POLYMERS USING BISMALEIMIDES AS CROSSLINKERS NATIONAL SCIENCE FOUNDATION 2016-07-21 US disclosed
US-20160208036-A1 SYNTHESIS OF CROSS-LINKED PLANT-OIL BASED POLYMERS USING BISMALEIMIDES AS CROSSLINKERS NATIONAL SCIENCE FOUNDATION 2016-07-21 US disclosed
WO-2015035156-A1 SYNTHESIS OF CROSS-LINKED PLANT-OIL BASED POLYMERS USING BISMALEIMIDES AS CROSSLINKERS THE UNIVERSITY OF AKRON (US) 2015-03-12 WO disclosed
US-8252862-B2 Silane coupling agents for filled rubbers BASF SE (DE) 2012-08-28 US disclosed
US-8252862-B2 Silane coupling agents for filled rubbers BASF SE (DE) 2012-08-28 US disclosed
US-8119710-B2 Filled rubber compounds with improved processability BASF SE (DE) 2012-02-21 US disclosed
US-8119710-B2 Filled rubber compounds with improved processability BASF SE (DE) 2012-02-21 US disclosed
EP-2190912-B1 SILANE COUPLING AGENTS FOR FILLED RUBBERS BASF SE (DE) 2011-11-23 EP disclosed
US-20100317778-A1 Filled Rubber Compounds with Improved Processability CIBA CORPORATION 2010-12-16 US disclosed
US-20100317778-A1 Filled Rubber Compounds with Improved Processability CIBA CORPORATION 2010-12-16 US disclosed
US-20100261826-A1 SILANE COUPLING AGENTS FOR FILLED RUBBERS BASF SE (DE) 2010-10-14 US disclosed
US-20100261826-A1 SILANE COUPLING AGENTS FOR FILLED RUBBERS BASF SE (DE) 2010-10-14 US disclosed
US-7723409-B2 Coupling agents between filler and elastomer CIBA SPECIALTY CHEM. CORP. (US) 2010-05-25 US disclosed
US-7723409-B2 Coupling agents between filler and elastomer CIBA SPECIALTY CHEM. CORP. (US) 2010-05-25 US disclosed
WO-2010006889-A2 COUPLING AGENTS FOR FILLED RUBBERS BASF SE (DE) 2010-01-21 WO disclosed
EP-1727858-B1 COUPLING AGENTS BETWEEN FILLER AND ELASTOMER BASF SE (DE) 2009-09-16 EP disclosed
WO-2009034016-A1 SILANE COUPLING AGENTS FOR FILLED RUBBERS BASF SE (CH) 2009-03-19 WO disclosed
US-20080287578-A1 Coupling Agents Between Filler and Elastomer CIBA SPECIALTY CHEMICALS CORP. 2008-11-20 US disclosed
US-20080287578-A1 Coupling Agents Between Filler and Elastomer CIBA SPECIALTY CHEMICALS CORP. 2008-11-20 US disclosed
WO-2007039416-A1 FILLED RUBBER COMPOUNDS WITH IMPROVED PROCESSABILITY CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2007-04-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100317778-A1 Filled Rubber Compounds with Improved Processability RER1, RIF1, REV1 ALDH1A1 1605/4885MEN1 1869/4885KMT2A 2949/4885
US-20100261826-A1 SILANE COUPLING AGENTS FOR FILLED RUBBERS RER1, REV1, RIOX2 ALDH1A1 1256/4885MEN1 3889/4885KMT2A 1874/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.