SCHEMBL822037

SCHEMBL822037

Cc1cccc(C(c2cccc(C)c2)(C(F)(F)F)C(F)(F)F)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 4/20 0.48
PTPN5 P54829 1/20 0.43
KIF11 P52732 2/20 0.41
CYP3A4 P08684 2/20 0.41
CYP2D6 P10635 2/20 0.41
CYP2C9 P11712 2/20 0.41
CYP2C19 P33261 2/20 0.41
KCNH2 Q12809 1/20 0.41
MAPK1 P28482 2/20 0.39
ALDH1A1 P00352 1/20 0.39
HTT P42858 2/20 0.39
MEN1 O00255 1/20 0.39
RAB9A P51151 1/20 0.39
KMT2A Q03164 1/20 0.39
NFE2L2 Q16236 1/20 0.39
CYP1A2 P05177 1/20 0.39
MAPT P10636 1/20 0.39
KCNK3 O14649 1/20 0.38
KCNK9 Q9NPC2 1/20 0.38
ESR1 P03372 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13618178 0.94 KIF11 (0.45) ACHEPTPN5KIF11CYP3A4CYP2D6
SCHEMBL822340 0.92 NFE2L2 (0.42) ACHEPTPN5KIF11CYP3A4CYP2D6
SCHEMBL12792076 0.90 ACHE (0.39) ACHEPTPN5KIF11CYP3A4CYP2D6
SCHEMBL9973083 0.89 TSHR (0.55) ACHEPTPN5KIF11CYP3A4CYP2D6
SCHEMBL19751380 0.86 RAPGEF4 (0.36) ACHEPTPN5KIF11CYP3A4CYP2D6
SCHEMBL15866566 0.86 PTPN5 (0.36) ACHEPTPN5KIF11CYP3A4CYP2D6
SCHEMBL17788975 0.86 ESR1 (0.49) ACHEPTPN5CYP2C19CYP1A2ESR1
SCHEMBL16191149 0.83 PTPN5 (0.40) ACHEPTPN5KIF11CYP3A4CYP2D6
SCHEMBL3277997 0.82 ACHE (0.48) ACHEPTPN5KIF11CYP3A4CYP2D6
SCHEMBL29749591 0.82 ACHE (0.48) ACHEPTPN5KIF11CYP3A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240069220-A1 SCINTILLATOR PANEL, RADIATION DETECTOR USING SAME, LINE CAMERA AND RADIATION INSPECTION DEVICE, AND INLINE INSPECTION METHOD AND INSPECTION METHOD USING SAME TORAY INDUSTRIES, INC. (JP) 2024-02-29 US disclosed
US-11814483-B2 Separation membrane comprising coating layer, method of preparing same, and battery using same SAMSUNG SDI CO., LTD. (KR) 2023-11-14 US disclosed
US-11814483-B2 Separation membrane comprising coating layer, method of preparing same, and battery using same SAMSUNG SDI CO., LTD. (KR) 2023-11-14 US disclosed
US-20230357505-A1 POLY(AMIDE-IMIDE) COPOLYMER, METHOD OF MANUFACTURING THE SAME, POLY(AMIDE-IMIDE) COPOLYMER FILM, WINDOW FOR DISPLAY DEVICE, AND DISPLAY DEVICE SAMSUNG ELECTRONICS CO LTD (KR) 2023-11-09 US disclosed
US-20230357505-A1 POLY(AMIDE-IMIDE) COPOLYMER, METHOD OF MANUFACTURING THE SAME, POLY(AMIDE-IMIDE) COPOLYMER FILM, WINDOW FOR DISPLAY DEVICE, AND DISPLAY DEVICE SAMSUNG ELECTRONICS CO LTD (KR) 2023-11-09 US disclosed
US-11739183-B2 Poly(amide-imide) copolymer, method of manufacturing the same, poly(amide-imide) copolymer film, window for display device, and display device SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-08-29 US disclosed
US-11739183-B2 Poly(amide-imide) copolymer, method of manufacturing the same, poly(amide-imide) copolymer film, window for display device, and display device SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-08-29 US disclosed
WO-2023005263-A1 RESIN COMPOSITION, RESIN FILM, AND DISPLAY DEVICE 吉林奥来德光电材料股份有限公司 2023-02-02 WO disclosed
US-11319514-B2 Composition for forming a coating film for removing foreign matters NISSAN CHEMICAL CORPORATION (JP) 2022-05-03 US disclosed
US-20210355279-A1 Polyimides FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. 2021-11-18 US disclosed
US-7598182-B2 having monomers of pyromellitic acid, 3,5-diaminobenzoic acid; use in a lithography for forming photoresist pattern NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2009-10-06 US disclosed
WO-2009113747-A1 PREPARATION METHOD OF POLYBENZOXAZOLES BY THERMAL REARRANGEMENT, POLYBENZOXAZOLES PREPARED THEREBY, AND GAS SEPARATION MEMBRANE COMPRISING THE SAME INDUSTRY-UNIVERSITY COOPERATION FOUNDATION, HANYANG UNIVERSITY (KR) 2009-09-17 WO disclosed
WO-2009107889-A1 POLYIMIDE-CO-POLYBENZOXAZOLE COPOLYMER, PREPARATION METHOD THEREOF, AND GAS SEPARATION MEMBRANE COMPRISING THE SAME INDUSTRY-UNIVERSITY COOPERATION FOUNDATION, HANYANG UNIVERSITY (KR) 2009-09-03 WO disclosed
US-7540991-B2 Molecular chains of the liquid crystalline polymer (e.g. polybenzoxazole, polybenzothiazole, and polybenzimidazole) having an ionic disosciative group and molecular chain orientated in a specific direction; allows permeation of hydrogen ions generated at a fuel electrode (anode) to cathode POLYMATECH CO., LTD. (JP) 2009-06-02 US disclosed
US-7540991-B2 Molecular chains of the liquid crystalline polymer (e.g. polybenzoxazole, polybenzothiazole, and polybenzimidazole) having an ionic disosciative group and molecular chain orientated in a specific direction; allows permeation of hydrogen ions generated at a fuel electrode (anode) to cathode POLYMATECH CO., LTD. (JP) 2009-06-02 US disclosed
US-7521744-B2 Resin-encapsulated semiconductor apparatus and process for its fabrication RENESAS TECHNOLOGY CORP. (JP) 2009-04-21 US disclosed
US-7521744-B2 Resin-encapsulated semiconductor apparatus and process for its fabrication RENESAS TECHNOLOGY CORP. (JP) 2009-04-21 US disclosed
US-20090092800-A1 COMPOSITION FOR PREPARING MODIFIED POLYIMIDE/CLAY NANOCOMPOSITES AND PREPARATION METHOD OF MODIFIED POLYMIDE/CLAY NANOCOMPOSITES USING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2009-04-09 US disclosed
US-20070048579-A1 Development of novel proton-conductive polymers for proton exchange membrane fuel cell (PEMFC) technology Board of Regents University and Community College System of Nevada 2007-03-01 US disclosed
US-20070004228-A1 Polyamide acid-containing composition for forming antireflective film NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2007-01-04 US disclosed