SCHEMBL9973083

SCHEMBL9973083

Cc1cccc(C(c2cccc(N)c2)(C(F)(F)F)C(F)(F)F)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.55
MAPK1 P28482 1/20 0.55
ACHE P22303 2/20 0.43
KIF11 P52732 3/20 0.41
CYP3A4 P08684 3/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
KCNH2 Q12809 1/20 0.38
CASP1 P29466 2/20 0.38
RECQL P46063 1/20 0.38
PTPN5 P54829 1/20 0.37
ALDH1A1 P00352 4/20 0.36
SMN1; SMN2 Q16637 2/20 0.35
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
KDM4E B2RXH2 2/20 0.34
MAPT P10636 2/20 0.34
HTR3E A5X5Y0 1/20 0.34
HTR3B O95264 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10493904 0.89 TSHR (0.68) TSHRMAPK1CYP3A4CASP1RECQL
SCHEMBL29373758 0.89 TSHR (0.68) TSHRMAPK1CYP3A4CASP1RECQL
SCHEMBL822037 0.89 ACHE (0.48) TSHRMAPK1ACHEKIF11CYP3A4
SCHEMBL126398 0.89 TSHR (0.68) TSHRMAPK1CYP3A4CASP1RECQL
SCHEMBL29799449 0.89 TSHR (0.68) TSHRMAPK1CYP3A4CASP1RECQL
SCHEMBL29492476 0.87 TSHR (0.65) TSHRMAPK1KIF11CYP3A4CASP1
Hydrochloric Acid SCHEMBL8646815 0.87 TSHR (0.65) TSHRMAPK1CYP3A4CASP1RECQL
SCHEMBL203354 0.87 TSHR (0.65) TSHRMAPK1KIF11CYP3A4CASP1
SCHEMBL201709 0.85 TSHR (0.63) TSHRMAPK1KIF11CYP3A4CASP1
SCHEMBL29492482 0.85 TSHR (0.63) TSHRMAPK1KIF11CYP3A4CASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230173798-A1 LAMINATED FILM, AND DISPLAY DEVICE INCLUDING SAME SAMSUNG ELECTRONICS CO LTD (KR) 2023-06-08 US disclosed
US-9975997-B2 Compositions, composites prepared therefrom, and films and electronic devices including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2018-05-22 US disclosed
US-9914811-B2 Window for display device and display device including the window SAMSUNG ELECTRONICS CO., LTD. (KR) 2018-03-13 US disclosed
US-9902814-B2 Transparent polymer film and electronic device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2018-02-27 US disclosed
US-20180022875-A1 COMPOSITION AND POLYAMIDEIMIDE COMPOSITE AND POLYAMIDEIMIDE FILM AND ELECTRONIC DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2018-01-25 US disclosed
US-9874657-B2 Compensation film and optical film and display device SAMSUNG ELECTRONICS CO., LTD. (KR) 2018-01-23 US disclosed
US-20170267821-A1 POLYIMIDE FILMS AND PRODUCTION METHODS THEREOF SAMSUNG ELECTRONICS CO LTD (KR) 2017-09-21 US disclosed
US-20170246773-A1 OPTICAL FILM AND METHOD OF PREPARING OPTICAL FILM SAMSUNG ELECTRONICS CO LTD (KR) 2017-08-31 US disclosed
US-9718943-B2 Composition of preparing polyimide-inorganic particle composite, polyimide-inorganic particle composite, and article including polyimide-inorganic particle composite SAMSUNG ELECTRONICS CO., LTD. (KR) 2017-08-01 US disclosed
US-20170199305-A1 COMPENSATION FILM AND OPTICAL FILM AND DISPLAY DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2017-07-13 US disclosed
US-20160009862-A1 TRANSPARENT POLYMER FILM AND ELECTRONIC DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-01-14 US disclosed
US-20150322218-A1 POLYIMIDE FILMS AND PRODUCTION METHODS THEREOF SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-11-12 US disclosed
US-20150152223-A1 POLYMER FOR OPTICAL FILM, AND OPTICAL FILM INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-06-04 US disclosed
US-20150147554-A1 COMPOSITION FOR PREPARING POLYIMIDE, POLYIMIDE, AND ARTICLE INCLUDING SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-05-28 US disclosed
US-20150025200-A1 COMPOSITION, POLYMER FILM, AND DISPLAY DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-01-22 US disclosed
US-20140371365-A1 POLYIMIDE PRECURSOR COMPOSITION, METHOD FOR PREPARING POLYIMIDE, POLYIMIDE PREPARED BY USING THE METHOD, AND FILM INCLUDING THE POLYIMIDE SAMSUNG ELECTRONICS CO., LTD. (KR) 2014-12-18 US disclosed
US-20140349098-A1 OPTICAL FILM AND METHOD OF PREPARING OPTICAL FILM SAMSUNG ELECTRONICS CO., LTD. (KR) 2014-11-27 US disclosed
US-8623968-B2 Polyimide precursor composition, method for preparing polyimide, polyimide prepared by using the method, and film including the polyimide SAMSUNG ELECTRONICS CO., LTD. (KR) 2014-01-07 US disclosed
US-20120157652-A1 POLYIMIDE PRECURSOR COMPOSITION, METHOD FOR PREPARING POLYIMIDE, POLYIMIDE PREPARED BY USING THE METHOD, AND FILM INCLUDING THE POLYIMIDE SAMSUNG ELECTRONICS CO., LTD. (KR) 2012-06-21 US disclosed
US-20100285994-A1 GOLD NANOPARTICLE COMPOSITION, DNA CHIP, NEAR INFRARED ABSORBENT, DRUG CARRIER FOR DRUG DELIVERY SYSTEM (DDS), COLORING AGENT, BIOSENSOR, COSMETIC, COMPOSITION FOR IN VIVO DIAGNOSIS AND COMPOSITION FOR THERAPEUTIC USE SHIGA UNIVERSITY OF MEDICAL SCIENCE (JP) 2010-11-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100285994-A1 GOLD NANOPARTICLE COMPOSITION, DNA CHIP, NEAR INFRARED ABSORBENT, DRUG CARRIER FOR DRUG DELIVERY SYSTEM (DDS), COLORING AGENT, BIOSENSOR, COSMETIC, COMPOSITION FOR IN VIVO DIAGNOSIS AND COMPOSITION FOR THERAPEUTIC USE DNMT1, DDB1, CUTA TSHR 1290/4885MAPK1 1771/4885ACHE 766/4885
US-20150025200-A1 COMPOSITION, POLYMER FILM, AND DISPLAY DEVICE DDT, DTD1, DRD1 TSHR 2891/4885MAPK1 525/4885ACHE 1537/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.