Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | HTR1A | P08908 | 4/20 | 0.52 |
| ▸ | MPO | P05164 | 3/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 8/20 | 0.42 |
| ▸ | HTR2C | P28335 | 6/20 | 0.42 |
| ▸ | HTR2B | P41595 | 4/20 | 0.42 |
| ▸ | HTR1D | P28221 | 2/20 | 0.42 |
| ▸ | HTR1B | P28222 | 2/20 | 0.42 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.42 |
| ▸ | HTR3B | O95264 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29445177 | 1.00 | GPR84 (0.65) | GPR84KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL21131303 | 0.88 | GPR84 (0.50) | GPR84KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL4720689 | 0.87 | KDM4E (0.49) | GPR84KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL1196112 | 0.84 | HTR1A (0.75) | GPR84KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL30483734 | 0.83 | HTR1A (0.74) | GPR84CYP2D6HTR1AMPOSLC6A4 | |
| SCHEMBL4633747 | 0.83 | MPO (0.68) | GPR84KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL25747532 | 0.83 | HTR1A (0.74) | GPR84CYP2D6HTR1AMPOSLC6A4 | |
| SCHEMBL24358682 | 0.79 | GPR84 (0.71) | GPR84KMT2AHTR1AMPOHTR2A | |
| SCHEMBL1241322 | 0.79 | GPR84 (0.67) | GPR84KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL3216581 | 0.79 | MPO (0.72) | GPR84KDM4EMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240067639-A1 | SMALL MOLECULES THAT TARGET THE RNA THAT CAUSES ALS | University of Florida Research Foundation, Incorporation (US) | 2024-02-29 | — | — | US | disclosed |
| US-20240067639-A1 | SMALL MOLECULES THAT TARGET THE RNA THAT CAUSES ALS | University of Florida Research Foundation, Incorporation (US) | 2024-02-29 | — | — | US | disclosed |
| WO-2008040974-A1 | INDOLES FOR USE AS DPP-IV INHIBITORS | PEAKDALE MOLECULAR LIMITED (GB) | 2008-04-10 | — | — | WO | disclosed |
| CN-1233630-C | N-substituted indole derivative preparation method | OCEAN UNIV CHINA (CN) | 2005-12-28 | — | — | CN | disclosed |
| CN-1544419-A | N-substituted indole derivative preparation method | 中国海洋大学 | 2004-11-10 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240067639-A1 | SMALL MOLECULES THAT TARGET THE RNA THAT CAUSES ALS | FUS, SNRPE, RRBP1 | GPR84 3306/4885KDM4E 1687/4885MEN1 3753/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.