Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 6/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.37 |
| ▸ | HSD17B13 | Q7Z5P4 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10162871 | 0.95 | ALDH1A1 (0.40) | KCNN3ALDH1A1MAPTMAPK1ALOX15 | |
| SCHEMBL14449909 | 0.90 | LIPG (0.41) | ALDH1A1MAPTMAPK1ALOX15L3MBTL1 | |
| SCHEMBL10162861 | 0.89 | ALDH1A1 (0.40) | ALDH1A1MAPTMAPK1ALOX15L3MBTL1 | |
| SCHEMBL8225378 | 0.89 | KCNN3 (0.43) | KCNN3ALDH1A1MAPTMAPK1KDM4E | |
| SCHEMBL8228853 | 0.89 | ADAMTS4 (0.40) | ALDH1A1MAPTMAPK1ALOX15L3MBTL1 | |
| SCHEMBL10162851 | 0.88 | MAPT (0.47) | ALDH1A1MAPTMAPK1ALOX15L3MBTL1 | |
| SCHEMBL10162873 | 0.86 | TP53 (0.44) | ALDH1A1MAPTALOX15L3MBTL1KDM4E | |
| SCHEMBL10162863 | 0.86 | ALDH1A1 (0.38) | ALDH1A1MAPTMAPK1ALOX15L3MBTL1 | |
| SCHEMBL8226340 | 0.85 | MMP13 (0.37) | ALDH1A1MAPTALOX15L3MBTL1KDM4E | |
| SCHEMBL8225958 | 0.85 | TP53 (0.44) | MAPTL3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007139856-A2 | HETEROBICYCLIC METALLOPROTEASE INHIBITORS | ALANTOS PHARMACEUTICALS, INC. (US) | 2007-12-06 | — | — | WO | disclosed |