Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 2/20 | 0.39 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.37 |
| ▸ | METTL14 | Q9HCE5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10162873 | 0.93 | TP53 (0.44) | LMNASMN1; SMN2MEN1KMT2ATSHR | |
| SCHEMBL10162840 | 0.93 | L3MBTL1 (0.48) | LMNASMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL8225958 | 0.92 | TP53 (0.44) | LMNASMN1; SMN2MEN1KMT2AL3MBTL1 | |
| SCHEMBL10162888 | 0.91 | MMP13 (0.39) | LMNAMEN1KMT2APKMPIK3CA | |
| SCHEMBL8227479 | 0.91 | MEN1 (0.44) | MEN1KMT2APIK3CAL3MBTL1MMP13 | |
| SCHEMBL10162862 | 0.91 | TP53 (0.40) | LMNASMN1; SMN2MEN1KMT2APIK3CA | |
| SCHEMBL8219951 | 0.91 | PIK3CA (0.42) | LMNASMN1; SMN2MEN1KMT2APKM | |
| SCHEMBL8225294 | 0.91 | ADAMTS4 (0.38) | LMNASMN1; SMN2HTTMEN1KMT2A | |
| SCHEMBL8221129 | 0.91 | TP53 (0.39) | LMNAMEN1KMT2APIK3CAALDH1A1 | |
| SCHEMBL10208197 | 0.91 | TP53 (0.39) | LMNASMN1; SMN2MEN1KMT2APIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007139856-A2 | HETEROBICYCLIC METALLOPROTEASE INHIBITORS | ALANTOS PHARMACEUTICALS, INC. (US) | 2007-12-06 | — | — | WO | disclosed |