Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL6ST | P40189 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | IDH1 | O75874 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4767695 | 0.87 | IL6ST (0.52) | IL6STHPGDALDH1A1STAT3PIK3CD | |
| SCHEMBL19183081 | 0.87 | IL6ST (0.52) | IL6STSMN1; SMN2ALDH1A1HTTSTAT3 | |
| SCHEMBL4767686 | 0.87 | IL6ST (0.52) | IL6STSMN1; SMN2ALDH1A1HTTSTAT3 | |
| SCHEMBL4775861 | 0.87 | IL6ST (0.52) | IL6STSMN1; SMN2ALDH1A1HTTSTAT3 | |
| SCHEMBL4770816 | 0.87 | IL6ST (0.52) | IL6STHPGDALDH1A1STAT3PIK3CD | |
| SCHEMBL9970272 | 0.87 | IL6ST (0.66) | IL6STHPGDALDH1A1STAT3PIK3CD | |
| SCHEMBL14523671 | 0.87 | IL6ST (0.66) | IL6STHPGDALDH1A1STAT3PIK3CD | |
| SCHEMBL13308119 | 0.86 | IL6ST (0.51) | IL6STHPGDALDH1A1STAT3PIK3CD | |
| SCHEMBL14960195 | 0.86 | IL6ST (0.51) | IL6STHPGDALDH1A1STAT3PIK3CD | |
| SCHEMBL7986602 | 0.81 | ALDH1A1 (0.47) | IL6STSMN1; SMN2HPGDALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080021024-A1 | Metalloprotease inhibitors | ALANTOS PHARMACEUTICALS HOLDING, INC. | 2008-01-24 | — | — | US | disclosed |
| US-20080021024-A1 | Metalloprotease inhibitors | ALANTOS PHARMACEUTICALS HOLDING, INC. | 2008-01-24 | — | — | US | disclosed |
| WO-2008002671-A2 | METALLOPROTEASE INHIBITORS | ALANTOS PHARMACEUTICALS HOLDING, INC. (US) | 2008-01-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080021024-A1 | Metalloprotease inhibitors | MMP2, MMP9, MMP3 | IL6ST 2563/4885SMN1; SMN2 3934/4885NPC1 1618/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.