SCHEMBL822573

SCHEMBL822573

O=C1c2ccc3c4c(ccc(c24)C(=O)N1CCc1ccccc1)C(=O)N(CCc1ccccc1)C3=O

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.75
MAPT P10636 4/20 0.75
RAB9A P51151 4/20 0.75
GAA P10253 3/20 0.75
KDM4E B2RXH2 2/20 0.75
SMN1; SMN2 Q16637 2/20 0.75
CASP3 P42574 1/20 0.69
CYP1B1 Q16678 3/20 0.68
KMT2A Q03164 4/20 0.61
MEN1 O00255 3/20 0.61
NPC1 O15118 2/20 0.61
POLB P06746 1/20 0.61
TAAR1 Q96RJ0 1/20 0.61
L3MBTL1 Q9Y468 2/20 0.59
TDP1 Q9NUW8 1/20 0.59
GSK3A P49840 1/20 0.58
GSK3B P49841 1/20 0.58
MGLL Q99685 1/20 0.58
ALDH2 P05091 1/20 0.57
ALDH3A1 P30838 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29361586 0.93 ALDH1A1 (0.67) ALDH1A1MAPTRAB9AGAAKDM4E
SCHEMBL1630714 0.93 ALDH1A1 (0.67) ALDH1A1MAPTRAB9AGAAKDM4E
SCHEMBL29724090 0.88 CASP3 (0.86) ALDH1A1MAPTRAB9AGAAKDM4E
SCHEMBL1142116 0.88 CASP3 (0.86) ALDH1A1MAPTRAB9AGAAKDM4E
SCHEMBL12431377 0.86 RAB9A (0.62) ALDH1A1MAPTRAB9AGAAKDM4E
SCHEMBL14303162 0.86 ALDH1A1 (0.58) ALDH1A1MAPTRAB9AGAAKDM4E
SCHEMBL14302320 0.86 ALDH1A1 (0.58) ALDH1A1MAPTRAB9AGAAKDM4E
SCHEMBL25269189 0.84 CYP1B1 (0.62) ALDH1A1MAPTRAB9AGAAKDM4E
SCHEMBL21894139 0.83 CYP1B1 (0.67) ALDH1A1MAPTRAB9AGAAKDM4E
SCHEMBL12744277 0.83 ALDH1A1 (0.59) ALDH1A1MAPTRAB9AGAAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9235145-B2 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2016-01-12 US disclosed
US-9235145-B2 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2016-01-12 US disclosed
US-8951701-B2 Composition for forming charge transporting film, electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2015-02-10 US disclosed
US-8951701-B2 Composition for forming charge transporting film, electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2015-02-10 US disclosed
US-20140321882-A1 COMPOSITION FOR FORMING CHARGE TRANSPORTING FILM, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2014-10-30 US disclosed
US-20140321882-A1 COMPOSITION FOR FORMING CHARGE TRANSPORTING FILM, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2014-10-30 US disclosed
US-8808952-B2 Composition for forming charge transporting film, electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2014-08-19 US disclosed
US-8808952-B2 Composition for forming charge transporting film, electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2014-08-19 US disclosed
US-20140205939-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2014-07-24 US disclosed
US-8748070-B2 Thiol group-containing charge transporting material, thiol group-containing charge transporting material-dissolving solution, photoelectric conversion device, electrophotographic photoreceptor, image forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2014-06-10 US disclosed
WO-2011137139-A1 AROMATIC AMIC ACIDS OR AMIC ESTERS AND COMPOSITIONS EASTMAN KODAK COMPANY (US) 2011-11-03 WO disclosed
US-20110269967-A1 AROMATIC AMIC ACIDS OR AMIC ESTERS AND COMPOSITIONS BANK OF AMERICA, N.A., AS AGENT 2011-11-03 US disclosed
US-20110269967-A1 AROMATIC AMIC ACIDS OR AMIC ESTERS AND COMPOSITIONS BANK OF AMERICA, N.A., AS AGENT 2011-11-03 US disclosed
US-7981719-B2 N,N′-di(arylalkyl)-substituted naphthalene-based tetracarboxylic diimide compounds as n-type semiconductor materials for thin film transistors EASTMAN KODAK COMPANY (US) 2011-07-19 US disclosed
US-7981719-B2 N,N′-di(arylalkyl)-substituted naphthalene-based tetracarboxylic diimide compounds as n-type semiconductor materials for thin film transistors EASTMAN KODAK COMPANY (US) 2011-07-19 US disclosed
EP-1872416-B1 SEMICONDUCTOR MATERIALS FOR THIN FILM TRANSISTORS EASTMAN KODAK CO (US) 2010-05-05 EP disclosed
US-20090261323-A1 N,N'-DI(ARYLALKYL)-SUBSTITUTED NAPHTHALENE-BASED TETRACARBOXYLIC DIIMIDE COMPOUNDS AS N-TYPE SEMICONDUCTOR MATERIALS FOR THIN FILM TRANSISTORS BANK OF AMERICA, N.A., AS AGENT 2009-10-22 US disclosed
US-20090261323-A1 N,N'-DI(ARYLALKYL)-SUBSTITUTED NAPHTHALENE-BASED TETRACARBOXYLIC DIIMIDE COMPOUNDS AS N-TYPE SEMICONDUCTOR MATERIALS FOR THIN FILM TRANSISTORS BANK OF AMERICA, N.A., AS AGENT 2009-10-22 US disclosed
US-7579619-B2 N,N′-di(arylalkyl)-substituted naphthalene-based tetracarboxylic diimide compounds as n-type semiconductor materials for thin film transistors EASTMAN KODAK COMPANY (US) 2009-08-25 US disclosed
US-7579619-B2 N,N′-di(arylalkyl)-substituted naphthalene-based tetracarboxylic diimide compounds as n-type semiconductor materials for thin film transistors EASTMAN KODAK COMPANY (US) 2009-08-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110269967-A1 AROMATIC AMIC ACIDS OR AMIC ESTERS AND COMPOSITIONS DDC, AADAC, MYOC ALDH1A1 745/4885MAPT 1597/4885RAB9A 1518/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.