SCHEMBL822601

SCHEMBL822601

C=CC(=O)OCC(CC)(COC(=O)C=C)COC(=O)c1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.63
HIF1A Q16665 2/20 0.63
THRB P10828 2/20 0.51
TDP1 Q9NUW8 3/20 0.49
SLC6A3 Q01959 2/20 0.49
CYP2D6 P10635 2/20 0.49
HTR1A P08908 1/20 0.49
SCN1A P35498 1/20 0.49
SCN5A Q14524 1/20 0.49
SCN2A Q99250 1/20 0.49
SCN3A Q9NY46 1/20 0.49
LMNA P02545 1/20 0.49
ALDH1A1 P00352 3/20 0.47
SMN1; SMN2 Q16637 3/20 0.47
TP53 P04637 1/20 0.47
CYP3A4 P08684 1/20 0.47
KMT2A Q03164 2/20 0.46
TSHR P16473 2/20 0.43
SLC6A2 P23975 1/20 0.42
CYP1A2 P05177 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL890407 0.95 MAPK1 (0.56) MAPK1HIF1ATHRBTDP1SLC6A3
SCHEMBL20192056 0.95 MAPK1 (0.56) MAPK1HIF1ATHRBTDP1SLC6A3
SCHEMBL16142139 0.92 MAPK1 (0.54) MAPK1HIF1ATHRBTDP1SLC6A3
SCHEMBL21164111 0.90 MAPK1 (0.51) MAPK1HIF1ATHRBTDP1SLC6A3
SCHEMBL21318094 0.89 ESR1 (0.51) MAPK1HIF1ATHRBTDP1CYP2D6
SCHEMBL30485505 0.88 ALDH1A1 (0.65) MAPK1HIF1ATHRBTDP1SLC6A3
SCHEMBL235921 0.87 MAPK1 (0.81) MAPK1HIF1ATDP1SLC6A3CYP2D6
SCHEMBL13946535 0.87 MAPK1 (0.61) MAPK1HIF1ATHRBTDP1SLC6A3
SCHEMBL69510 0.87 MAPK1 (0.56) MAPK1HIF1ATHRBTDP1SLC6A3
SCHEMBL12009414 0.87 MAPK1 (0.56) MAPK1HIF1ATHRBTDP1SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 166 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11319390-B2 Poly(ethylene glycol) methacrylate microgels, preparation method and uses LVMH RECHERCHE (FR) 2022-05-03 US claimed
US-20250333476-A1 ENGINEERED CD47 PROTEINS AND USES THEREOF SANA BIOTECHNOLOGY INC (US) 2025-10-30 US disclosed
US-20250230470-A1 SAFETY SWITCHES TO CONTROL IN VITRO AND IN VIVO PROLIFERATION OF CELL THERAPY PRODUCTS SANA BIOTECHNOLOGY, INC. 2025-07-17 US disclosed
WO-2025151838-A1 SAFETY SWITCHES TO CONTROL IN VITRO AND IN VIVO PROLIFERATION OF CELL THERAPY PRODUCTS SANA BIOTECHNOLOGY, INC. (US) 2025-07-17 WO disclosed
US-12351667-B2 Separator for electrochemical energy accumulators and converters CARL FREUDENBERG KG (DE) 2025-07-08 US disclosed
US-20250127820-A1 GENETICALLY MODIFIED CELLS FOR ALLOGENEIC CELL THERAPY TO REDUCE INSTANT BLOOD MEDIATED INFLAMMATORY REACTIONS SANA BIOTECHNOLOGY, INC. (US) 2025-04-24 US disclosed
WO-2025054202-A1 METHOD OF SCREENING A SAMPLE COMPRISING A TRANSGENE WITH A UNIQUE BARCODE SANA BIOTECHNOLOGY, INC. (US) 2025-03-13 WO disclosed
US-12242188-B2 Photosensitive resin composition for imprinting, cured article and optical element ECHEM SOLUTIONS CORP. (TW) 2025-03-04 US disclosed
CN-119372151-A Cells differentiated from immune engineered pluripotent cells 加利福尼亚大学董事会 2025-01-28 CN disclosed
EP-3975927-B1 MUCOADHESIVE MICROGEL COMPOSITIONS AND METHODS FOR USING THE SAME UNIV LELAND STANFORD JUNIOR (US) 2025-01-22 EP disclosed
WO-2009056955-A1 AMINE-BEARING PHOSPHOLIPIDS (ABPS), THEIR SYNTHESIS AND USE UNIVERSITY OF BASEL (CH) 2009-05-07 WO disclosed
US-20080242626-A1 End-Modified Poly(beta-amino esters) and Uses Thereof MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2008-10-02 US disclosed
US-20080242626-A1 End-Modified Poly(beta-amino esters) and Uses Thereof MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2008-10-02 US disclosed
US-7427394-B2 Delivering labile agents; buffering effect; transfecting nucleic acids; nontoxic MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2008-09-23 US disclosed
US-7427394-B2 Delivering labile agents; buffering effect; transfecting nucleic acids; nontoxic MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2008-09-23 US disclosed
WO-2008109105-A2 METHODS AND COMPOSITIONS FOR IMPROVED THERAPEUTIC EFFECTS WITH SIRNA FLAGSHIP VENTURES (US) 2008-09-12 WO disclosed
US-20080145338-A1 Acrylate-terminated poly(beta-amino esters); high throughput assay; biocompatability NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2008-06-19 US disclosed
US-20080145338-A1 Acrylate-terminated poly(beta-amino esters); high throughput assay; biocompatability NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2008-06-19 US disclosed
WO-2008011561-A2 END-MODIFIED POLY(BETA-AMINO ESTERS) AND USES THEREOF MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2008-01-24 WO disclosed
WO-2007143659-A2 CROSSLINKED, DEGRADABLE POLYMERS AND USES THEREOF MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2007-12-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080145338-A1 Acrylate-terminated poly(beta-amino esters); high throughput assay; biocompatability ACP1, ILK, BCAT2 MAPK1 2083/4885HIF1A 2413/4885THRB 867/4885
US-20080242626-A1 End-Modified Poly(beta-amino esters) and Uses Thereof PARN, PARG, POLL MAPK1 4777/4885HIF1A 2383/4885THRB 3058/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.