SCHEMBL822757

SCHEMBL822757

O=C(O)c1ccc2c3ccc(C(=O)NC4CCCC4)c4c(C(=O)O)ccc(c5ccc(C(=O)NC6CCCC6)c1c25)c43

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GAA P10253 4/20 0.50
ALDH1A1 P00352 4/20 0.49
KDM4E B2RXH2 3/20 0.49
RAB9A P51151 4/20 0.49
NPC1 O15118 4/20 0.49
LMNA P02545 3/20 0.49
HPGD P15428 3/20 0.49
KMT2A Q03164 2/20 0.49
MEN1 O00255 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49
HTT P42858 1/20 0.49
MAPT P10636 2/20 0.46
PKM P14618 1/20 0.46
GLA P06280 1/20 0.46
MAPK1 P28482 1/20 0.46
CYP1A2 P05177 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16351826 0.98 NPC1 (0.51) GAAALDH1A1KDM4ERAB9ANPC1
SCHEMBL823149 0.98 NPC1 (0.51) GAAALDH1A1KDM4ERAB9ANPC1
SCHEMBL4930405 0.98 NPC1 (0.51) GAAALDH1A1KDM4ERAB9ANPC1
SCHEMBL5053780 0.94 GAA (0.55) GAAALDH1A1KDM4ERAB9ANPC1
SCHEMBL12021895 0.94 GAA (0.55) GAAALDH1A1KDM4ERAB9ANPC1
SCHEMBL822571 0.94 GAA (0.55) GAAALDH1A1KDM4ERAB9ANPC1
SCHEMBL2159871 0.92 NPC1 (0.57) GAAALDH1A1KDM4ERAB9ANPC1
SCHEMBL823228 0.92 NPC1 (0.57) GAAALDH1A1KDM4ERAB9ANPC1
SCHEMBL12021902 0.92 NPC1 (0.57) GAAALDH1A1KDM4ERAB9ANPC1
SCHEMBL12038243 0.89 GAA (0.42) GAAALDH1A1KDM4ERAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8530270-B2 Methods of preparing semiconductive compositions and devices EASTMAN KODAK COMPANY (US) 2013-09-10 US disclosed
US-8530270-B2 Methods of preparing semiconductive compositions and devices EASTMAN KODAK COMPANY (US) 2013-09-10 US disclosed
US-8411489-B2 Semiconducting devices and methods of preparing EASTMAN KODAK COMPANY (US) 2013-04-02 US disclosed
US-8411489-B2 Semiconducting devices and methods of preparing EASTMAN KODAK COMPANY (US) 2013-04-02 US disclosed
US-8314265-B2 Aromatic amic acids or amic esters and compositions EASTMAN KODAK COMPANY (US) 2012-11-20 US disclosed
US-8314265-B2 Aromatic amic acids or amic esters and compositions EASTMAN KODAK COMPANY (US) 2012-11-20 US disclosed
US-20110269967-A1 AROMATIC AMIC ACIDS OR AMIC ESTERS AND COMPOSITIONS BANK OF AMERICA, N.A., AS AGENT 2011-11-03 US disclosed
US-20110269967-A1 AROMATIC AMIC ACIDS OR AMIC ESTERS AND COMPOSITIONS BANK OF AMERICA, N.A., AS AGENT 2011-11-03 US disclosed
WO-2011137137-A1 SEMICONDUCTING ARTICLES EASTMAN KODAK COMPANY (US) 2011-11-03 WO disclosed
US-20110269265-A1 METHODS OF PREPARING SEMICONDUCTIVE COMPOSITIONS AND DEVICES KODAK REALTY INC. 2011-11-03 US disclosed
US-20110269265-A1 METHODS OF PREPARING SEMICONDUCTIVE COMPOSITIONS AND DEVICES KODAK REALTY INC. 2011-11-03 US disclosed
US-20110266523-A1 SEMICONDUCTING DEVICES AND METHODS OF PREPARING BANK OF AMERICA, N.A., AS AGENT 2011-11-03 US disclosed
US-20110266523-A1 SEMICONDUCTING DEVICES AND METHODS OF PREPARING BANK OF AMERICA, N.A., AS AGENT 2011-11-03 US disclosed
US-20110269966-A1 SEMICONDUCTING ARTICLES CITICORP NORTH AMERICA, INC., AS AGENT 2011-11-03 US disclosed
US-20110269966-A1 SEMICONDUCTING ARTICLES CITICORP NORTH AMERICA, INC., AS AGENT 2011-11-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110269966-A1 SEMICONDUCTING ARTICLES ALAD, PORCN, DDC GAA 2404/4885ALDH1A1 508/4885KDM4E 1041/4885
US-20110269967-A1 AROMATIC AMIC ACIDS OR AMIC ESTERS AND COMPOSITIONS DDC, AADAC, MYOC GAA 2124/4885ALDH1A1 745/4885KDM4E 664/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.