Sugi Predict

Sugi Predict / Compounds / SCHEMBL823149

SCHEMBL823149

SCHEMBL823149

O=C(O)c1ccc2c3ccc(C(=O)NC4CCCCC4)c4c(C(=O)O)ccc(c5ccc(C(=O)NC6CCCCC6)c1c25)c43

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NPC1 O15118 6/20 0.51
▸ RAB9A P51151 6/20 0.51
▸ ALDH1A1 P00352 4/20 0.51
▸ LMNA P02545 3/20 0.51
▸ KDM4E B2RXH2 2/20 0.51
▸ KMT2A Q03164 2/20 0.51
▸ HTT P42858 2/20 0.51
▸ HPGD P15428 2/20 0.51
▸ SMN1; SMN2 Q16637 2/20 0.51
▸ MEN1 O00255 1/20 0.51
▸ NPSR1 Q6W5P4 1/20 0.51
▸ GAA P10253 4/20 0.51
▸ GLA P06280 1/20 0.48
▸ MAPK1 P28482 1/20 0.48
▸ MAPT P10636 1/20 0.47
▸ APOBEC3G Q9HC16 1/20 0.46
▸ CYP1A2 P05177 1/20 0.45
▸ CYP2C19 P33261 1/20 0.45
▸ MAOB P27338 1/20 0.45
▸ SGMS2 Q8NHU3 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4930405 1.00 NPC1 (0.51) NPC1RAB9AALDH1A1LMNAKDM4E
SCHEMBL16351826 1.00 NPC1 (0.51) NPC1RAB9AALDH1A1LMNAKDM4E
SCHEMBL822757 0.98 GAA (0.50) NPC1RAB9AALDH1A1LMNAKDM4E
SCHEMBL12021902 0.94 NPC1 (0.57) NPC1RAB9AALDH1A1LMNAKDM4E
SCHEMBL2159871 0.94 NPC1 (0.57) NPC1RAB9AALDH1A1LMNAKDM4E
SCHEMBL823228 0.94 NPC1 (0.57) NPC1RAB9AALDH1A1LMNAKDM4E
SCHEMBL12021895 0.92 GAA (0.55) NPC1RAB9AALDH1A1LMNAKDM4E
SCHEMBL5053780 0.92 GAA (0.55) NPC1RAB9AALDH1A1LMNAKDM4E
SCHEMBL822571 0.92 GAA (0.55) NPC1RAB9AALDH1A1LMNAKDM4E
SCHEMBL12038246 0.90 ALDH1A1 (0.43) NPC1RAB9AALDH1A1LMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8530270-B2 Methods of preparing semiconductive compositions and devices EASTMAN KODAK COMPANY (US) 2013-09-10 — — US disclosed
US-8411489-B2 Semiconducting devices and methods of preparing EASTMAN KODAK COMPANY (US) 2013-04-02 — — US disclosed
US-8314265-B2 Aromatic amic acids or amic esters and compositions EASTMAN KODAK COMPANY (US) 2012-11-20 — — US disclosed
US-20110269967-A1 AROMATIC AMIC ACIDS OR AMIC ESTERS AND COMPOSITIONS BANK OF AMERICA, N.A., AS AGENT 2011-11-03 — — US disclosed
US-20110266523-A1 SEMICONDUCTING DEVICES AND METHODS OF PREPARING BANK OF AMERICA, N.A., AS AGENT 2011-11-03 — — US disclosed
US-20110269265-A1 METHODS OF PREPARING SEMICONDUCTIVE COMPOSITIONS AND DEVICES KODAK REALTY INC. 2011-11-03 — — US disclosed
US-20110269966-A1 SEMICONDUCTING ARTICLES CITICORP NORTH AMERICA, INC., AS AGENT 2011-11-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110269966-A1 SEMICONDUCTING ARTICLES ALAD, PORCN, DDC NPC1 2148/4885RAB9A 2482/4885ALDH1A1 508/4885
US-20110269967-A1 AROMATIC AMIC ACIDS OR AMIC ESTERS AND COMPOSITIONS DDC, AADAC, MYOC NPC1 2077/4885RAB9A 1518/4885ALDH1A1 745/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.