SCHEMBL822834

SCHEMBL822834

Cc1ccc(C2(c3ccc(C)cc3)OC(=O)c3ccccc32)cc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CFTR P13569 1/20 0.73
GOPC Q9HD26 1/20 0.73
LMNA P02545 5/20 0.70
MAPT P10636 4/20 0.70
POLB P06746 3/20 0.70
TDP1 Q9NUW8 3/20 0.70
MEN1 O00255 3/20 0.70
KMT2A Q03164 3/20 0.70
CYP3A4 P08684 3/20 0.70
SMN1; SMN2 Q16637 2/20 0.70
GPR55 Q9Y2T6 2/20 0.70
ALDH1A1 P00352 2/20 0.70
HSD17B10 Q99714 2/20 0.70
TP53 P04637 2/20 0.70
ALOX15 P16050 2/20 0.70
ESR1 P03372 1/20 0.70
TYMS P04818 1/20 0.70
TSHR P16473 1/20 0.70
ESR2 Q92731 1/20 0.70
NPSR1 Q6W5P4 3/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12715937 0.92 LMNA (0.85) CFTRGOPCLMNAMAPTPOLB
SCHEMBL19010401 0.92 CFTR (0.63) CFTRGOPCLMNAMAPTPOLB
SCHEMBL18161910 0.89 CFTR (0.59) CFTRGOPCLMNAMAPTPOLB
SCHEMBL13869867 0.88 LMNA (0.60) CFTRGOPCLMNAMAPTPOLB
SCHEMBL25457206 0.86 CFTR (0.55) CFTRGOPCLMNAMAPTPOLB
SCHEMBL13882161 0.86 CFTR (0.55) CFTRGOPCLMNAMAPTPOLB
SCHEMBL3886398 0.85 CFTR (1.00) CFTRGOPCLMNAMAPTPOLB
SCHEMBL25005560 0.85 CFTR (0.54) CFTRGOPCLMNAMAPTPOLB
SCHEMBL16303127 0.84 LMNA (0.68) CFTRGOPCLMNAMAPTPOLB
Phenolphthalein SCHEMBL9755053 0.83 MAPT (0.93) CFTRGOPCLMNAMAPTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240016699-A1 PHARMACEUTICAL PACKAGES WITH COATINGS COMPRISING POLYCYANURATES CORNING INC (US) 2024-01-18 US disclosed
US-20240016699-A1 PHARMACEUTICAL PACKAGES WITH COATINGS COMPRISING POLYCYANURATES CORNING INC (US) 2024-01-18 US disclosed
US-11707411-B2 Pharmaceutical packages with coatings comprising polycyanurates CORNING INCORPORATED (US) 2023-07-25 US disclosed
US-11707411-B2 Pharmaceutical packages with coatings comprising polycyanurates CORNING INCORPORATED (US) 2023-07-25 US disclosed
US-20230123589-A1 MOLECULAR MOBILITY ENHANCER OR MOLECULAR DRYING ENHANCER TEKDRY INTERNATIONAL, INC. 2023-04-20 US disclosed
EP-4116356-A1 AROMATIC POLYSULFONE COPOLYMERS Ht Materials Corporation (US) 2023-01-11 EP disclosed
WO-2021154959-A1 MOLECULAR MOBILITY ENHANCER OR MOLECULAR DRYING ENHANCER TEKDRY INTERNATIONAL, INC. (US) 2021-08-05 WO disclosed
WO-2021109396-A1 POLYETHER ETHER ANILINE-ETHER ETHER SULFONE COPOLYMER, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF, AND POLYETHER ETHER KETONE-ETHER ETHER SULFONE COPOLYMER AND PREPARATION METHOD THEREFOR 中国科学院长春应用化学研究所 2021-06-10 WO disclosed
US-20210038474-A1 PHARMACEUTICAL PACKAGES WITH COATINGS COMPRISING POLYCYANURATES CORNING INCORPORATED 2021-02-11 US disclosed
WO-2020232597-A1 DIAMINE COMPOUND, PREPARATION METHOD THEREFOR, THERMOSETTING RESIN COMPOSITION, AND APPLICATION 广东生益科技股份有限公司 (CN) 2020-11-26 WO disclosed
US-20080165421-A1 LIGHT SELECTIVE TRANSMISSION FILTER NIPPON SHOKUBAI CO., LTD. (JP) 2008-07-10 US disclosed
US-7375178-B2 High refractive index thermoplastic polyphosphonates ESSILOR INTERNATIONAL (FR) 2008-05-20 US disclosed
US-7375178-B2 High refractive index thermoplastic polyphosphonates ESSILOR INTERNATIONAL (FR) 2008-05-20 US disclosed
US-7282320-B2 Apparatus for three-dimensional optical data storage and retrieval THE TRUSTEES OF BOSTON COLLEGE (US) 2007-10-16 US disclosed
US-7258918-B2 Method for connecting electrodes, surface-treated wiring board and adhesive film used in the method, and electrode-connected structure HITACHI CHEMICAL CO., LTD. (JP) 2007-08-21 US disclosed
US-7258918-B2 Method for connecting electrodes, surface-treated wiring board and adhesive film used in the method, and electrode-connected structure HITACHI CHEMICAL CO., LTD. (JP) 2007-08-21 US disclosed
US-20070155951-A1 High refractive index thermoplastic polyphosphonates VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY 2007-07-05 US disclosed
US-20070155951-A1 High refractive index thermoplastic polyphosphonates VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY 2007-07-05 US disclosed
US-20070148586-A1 Hardmask compositions for resist underlayer film and method for producing semiconductor integrated circuit device using the same CHEIL INDUSTRIES, INC. (KR) 2007-06-28 US disclosed
EP-1095978-B1 Additiv mixture for improvement of mechanic properties of polymers CIBA SC HOLDING AG (CH) 2007-02-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230123589-A1 MOLECULAR MOBILITY ENHANCER OR MOLECULAR DRYING ENHANCER SNRPE, MTREX, MMP20 CFTR 180/4885GOPC 3520/4885LMNA 3216/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.