SCHEMBL8229296

SCHEMBL8229296

CC(C)c1ccnc(Br)c1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.35
IDO1 P14902 1/20 0.35
CHRNA7 P36544 1/20 0.35
TRPA1 O75762 1/20 0.34
PTGS1 P23219 1/20 0.34
CACNA1C Q13936 1/20 0.34
AURKA O14965 1/20 0.34
DAPK3 O43293 1/20 0.34
JAK2 O60674 1/20 0.34
MAP4K4 O95819 1/20 0.34
PAK4 O96013 1/20 0.34
ABL1 P00519 1/20 0.34
LCK P06239 1/20 0.34
FYN P06241 1/20 0.34
CSF1R P07333 1/20 0.34
RET P07949 1/20 0.34
IGF1R P08069 1/20 0.34
FLT1 P17948 1/20 0.34
LTK P29376 1/20 0.34
KDR P35968 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29935566 0.87 IDO1 (0.33) IDO1CYP3A4HDAC8CYP2C19KDM1A
SCHEMBL28759287 0.84 IDO1 (0.34) IDO1CYP3A4HDAC8CYP2C19KDM1A
SCHEMBL31032205 0.83 PLG (0.41) IDO1ALDH1A1CYP3A4HDAC8CYP2C19
SCHEMBL17000191 0.83 IDO1 (0.33) IDO1CYP3A4HDAC8CYP2C19KDM1A
SCHEMBL29867137 0.83 PLG (0.41) IDO1ALDH1A1CYP3A4HDAC8CYP2C19
SCHEMBL568609 0.83 PLG (0.41) IDO1ALDH1A1CYP3A4HDAC8CYP2C19
SCHEMBL3466298 0.83 ADRB2 (0.35) IDO1MAP4K4GSK3AGSK3BCDK9
SCHEMBL3464147 0.83 ADRB2 (0.35) IDO1MAP4K4GSK3AGSK3BCDK9
SCHEMBL21200276 0.83 PLG (0.41) IDO1ALDH1A1CYP3A4HDAC8CYP2C19
SCHEMBL14211416 0.83 ADRB2 (0.35) IDO1MAP4K4GSK3AGSK3BCDK9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3960747-B1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO LTD (KR) 2025-12-10 EP disclosed
US-12492218-B2 Organometallic compound, organic light-emitting device including the same, and electronic apparatus including the organic light-emitting device SAMSUNG ELECTRONICS CO., LTD. (KR) 2025-12-09 US disclosed
US-12448402-B2 Organometallic compound, organic light-emitting device including the same, and diagnostic composition including the organometallic compound SAMSUNG ELECTRONICS CO., LTD. (KR) 2025-10-21 US disclosed
EP-4016656-B1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND DIAGNOSTIC COMPOSITION INCLUDING THE ORGANOMETALLIC COMPOUND SAMSUNG ELECTRONICS CO LTD (KR) 2025-09-03 EP disclosed
US-12391714-B2 Organometallic compound, organic light-emitting device including the same, and diagnostic composition including the organometallic compound SAMSUNG ELECTRONICS CO., LTD. (KR) 2025-08-19 US disclosed
CN-116553993-B Method for producing alpha-olefin 中化学科学技术研究有限公司 2025-01-03 CN disclosed
CN-118955569-A Organic electroluminescent material and organic electroluminescent device 吉林奥来德光电材料股份有限公司 2024-11-15 CN disclosed
US-12004416-B2 Organometallic compound and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2024-06-04 US disclosed
CN-117659088-A Organic ligand containing NPN and PNP structures, preparation method thereof, catalyst and ethylene oligomerization method 中化学科学技术研究有限公司 2024-03-08 CN disclosed
CN-117659087-A Binuclear metal complex containing NP structure, preparation method and application thereof 中化学科学技术研究有限公司 2024-03-08 CN disclosed
US-8034811-B2 Hydroxamic acid esters and pharmaceutical use thereof LEO PHARMA A/S (DK) 2011-10-11 US disclosed
US-20110224190-A1 PIPERIDIN-4-YL AZETIDINE DERIVATIVES AS JAK1 INHIBITORS INCYTE CORPORATION 2011-09-15 US disclosed
US-20110224190-A1 PIPERIDIN-4-YL AZETIDINE DERIVATIVES AS JAK1 INHIBITORS INCYTE CORPORATION 2011-09-15 US disclosed
US-20100323887-A1 MESOIONIC PESTICIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 2010-12-23 US disclosed
US-20100113439-A1 Antifungal agents MERCK & CO., INC. (US) 2010-05-06 US disclosed
US-20090102363-A1 METAL COMPLEX COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2009-04-23 US disclosed
US-20090102363-A1 METAL COMPLEX COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2009-04-23 US disclosed
US-20070244117-A1 Novel Hydroxamic Acid Esters and Pharmaceutical Use Thereof LEO PHARMA A/S (DK) 2007-10-18 US disclosed
US-20070142369-A1 Combination of an H3 antagonist/inverse agonist and an appetite suppressant SCHERING CORPORATION 2007-06-21 US disclosed
US-7220735-B2 Benzimidazolone histamine H3 antagonists SCHERING CORPORATION (US) 2007-05-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12492218-B2 Organometallic compound, organic light-emitting device including the same, and electronic apparatus including the organic light-emitting device L1CAM, FOXM1, CCNT1 LMNA 612/4885IDO1 1289/4885CHRNA7 3113/4885
US-20070142369-A1 Combination of an H3 antagonist/inverse agonist and an appetite suppressant CNR2, GPR119, GLP1R LMNA 4032/4885IDO1 183/4885CHRNA7 167/4885
US-20090102363-A1 METAL COMPLEX COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME EPCAM, L1CAM, EMC2 LMNA 1800/4885IDO1 3194/4885CHRNA7 333/4885
US-20100113439-A1 Antifungal agents GMDS, GBA3, UGGT1 LMNA 3066/4885IDO1 857/4885CHRNA7 4618/4885
US-12448402-B2 Organometallic compound, organic light-emitting device including the same, and diagnostic composition including the organometallic compound L1CAM, NOM1, LEF1 LMNA 1217/4885IDO1 795/4885CHRNA7 4169/4885
US-20100323887-A1 MESOIONIC PESTICIDES DDT, CHRM1, CHRM3 LMNA 4228/4885IDO1 31/4885CHRNA7 86/4885
US-12004416-B2 Organometallic compound and organic light-emitting device including the same L1CAM, FOXM1, LEF1 LMNA 1654/4885IDO1 690/4885CHRNA7 3541/4885
US-12391714-B2 Organometallic compound, organic light-emitting device including the same, and diagnostic composition including the organometallic compound L1CAM, FOXM1, CYBA LMNA 1153/4885IDO1 513/4885CHRNA7 2519/4885
US-20070244117-A1 Novel Hydroxamic Acid Esters and Pharmaceutical Use Thereof F9, F12, HDAC9 LMNA 3439/4885IDO1 3029/4885CHRNA7 4641/4885
US-20110224190-A1 PIPERIDIN-4-YL AZETIDINE DERIVATIVES AS JAK1 INHIBITORS JAK1, JAK2, JAK3 LMNA 4748/4885IDO1 104/4885CHRNA7 4806/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.