Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | PLK1 | P53350 | 4/20 | 0.42 |
| ▸ | NEU3 | Q9UQ49 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11520918 | 1.00 | CYP1A2 (0.54) | CYP1A2PLK1NEU3GAABRD4 | |
| SCHEMBL2100060 | 1.00 | CYP1A2 (0.54) | CYP1A2PLK1NEU3GAABRD4 | |
| SCHEMBL30101142 | 1.00 | CYP1A2 (0.54) | CYP1A2PLK1NEU3GAABRD4 | |
| SCHEMBL823142 | 0.92 | CYP1A2 (0.64) | CYP1A2PLK1NEU3GAABRD4 | |
| SCHEMBL12021877 | 0.92 | CYP1A2 (0.64) | CYP1A2PLK1NEU3GAABRD4 | |
| SCHEMBL4959993 | 0.92 | CYP1A2 (0.64) | CYP1A2PLK1NEU3GAABRD4 | |
| SCHEMBL12038232 | 0.87 | CYP1A2 (0.41) | CYP1A2PLK1NEU3GAABRD4 | |
| SCHEMBL12180026 | 0.87 | CYP1A2 (0.41) | CYP1A2PLK1NEU3GAABRD4 | |
| SCHEMBL12038247 | 0.87 | CYP1A2 (0.41) | CYP1A2PLK1NEU3GAABRD4 | |
| SCHEMBL30141 | 0.83 | CYP1A2 (0.78) | CYP1A2GAANR4A2KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8314265-B2 | Aromatic amic acids or amic esters and compositions | EASTMAN KODAK COMPANY (US) | 2012-11-20 | — | — | US | disclosed |
| US-20110269967-A1 | AROMATIC AMIC ACIDS OR AMIC ESTERS AND COMPOSITIONS | BANK OF AMERICA, N.A., AS AGENT | 2011-11-03 | — | — | US | disclosed |
| US-20110269966-A1 | SEMICONDUCTING ARTICLES | CITICORP NORTH AMERICA, INC., AS AGENT | 2011-11-03 | — | — | US | disclosed |
| US-20110269265-A1 | METHODS OF PREPARING SEMICONDUCTIVE COMPOSITIONS AND DEVICES | KODAK REALTY INC. | 2011-11-03 | — | — | US | disclosed |
| US-20110266523-A1 | SEMICONDUCTING DEVICES AND METHODS OF PREPARING | BANK OF AMERICA, N.A., AS AGENT | 2011-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110269966-A1 | SEMICONDUCTING ARTICLES | ALAD, PORCN, DDC | CYP1A2 498/4885PLK1 4353/4885NEU3 3664/4885 |
| US-20110269967-A1 | AROMATIC AMIC ACIDS OR AMIC ESTERS AND COMPOSITIONS | DDC, AADAC, MYOC | CYP1A2 155/4885PLK1 4884/4885NEU3 2145/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.