Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SFRP1 | Q8N474 | 9/20 | 0.51 |
| ▸ | WNT3 | P56703 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | UBE2M | P61081 | 1/20 | 0.44 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.44 |
| ▸ | IDH2 | P48735 | 2/20 | 0.44 |
| ▸ | PKLR | P30613 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3485050 | 0.83 | HPGD (0.48) | MEN1KMT2ANPSR1UBE2MDCUN1D1 | |
| SCHEMBL5325345 | 0.74 | USP2 (0.49) | MEN1KMT2ANPSR1UBE2MDCUN1D1 | |
| SCHEMBL8234373 | 0.73 | LMNA (0.49) | SFRP1MEN1KMT2AHTR1AHTR7 | |
| SCHEMBL8269931 | 0.73 | EPHX2 (0.44) | SFRP1WNT3HTR1AHTR7IDH2 | |
| SCHEMBL4281416 | 0.71 | STS (0.60) | SFRP1WNT3HTR1AHTR7HDAC8 | |
| SCHEMBL2420848 | 0.71 | CA1 (0.62) | KMT2ANPSR1HTR1AHTR7IDH2 | |
| SCHEMBL3485323 | 0.71 | ALDH1A1 (0.49) | SFRP1WNT3HTR1AHTR7IDH2 | |
| SCHEMBL23052376 | 0.70 | HTR1A (0.61) | SFRP1HTR1AHTR7PKLRHPGD | |
| SCHEMBL8044831 | 0.69 | CACNA1B (0.60) | MEN1KMT2ANPSR1HPGDHTT | |
| SCHEMBL5503404 | 0.69 | SFRP1 (0.45) | SFRP1WNT3HTR1AHTR7HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007118853-A1 | BENZENESULFONAMIDE COMPOUNDS AND THEIR USE AS BLOCKERS OF CALCIUM CHANNELS | EURO-CELTIQUE S.A. (LU) | 2007-10-25 | — | — | WO | disclosed |