Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.36 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.36 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8233962 | 0.82 | ALDH1A1 (0.45) | KDM4EADORA3ADORA2AADORA1ALDH1A1 | |
| SCHEMBL8233443 | 0.82 | ADORA1 (0.42) | KDM4EADORA3ADORA2AADORA1HPGD | |
| SCHEMBL5338305 | 0.81 | MAPT (0.48) | KDM4EADORA3ADORA2AADORA1ALDH1A1 | |
| SCHEMBL8233396 | 0.81 | ADORA1 (0.41) | KDM4EADORA3ADORA2AADORA1HPGD | |
| SCHEMBL5334907 | 0.75 | GSK3B (0.43) | KDM4EALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL8227750 | 0.74 | MAPT (0.46) | KDM4EALDH1A1TMIGD3RAB9ASMN1; SMN2 | |
| SCHEMBL8236528 | 0.74 | CXCR3 (0.41) | KDM4EHPGDALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL8235194 | 0.72 | MAPT (0.49) | KDM4EHPGDALDH1A1POLB | |
| SCHEMBL8234236 | 0.71 | KMT2A (0.44) | KDM4EHPGDALDH1A1SMN1; SMN2POLB | |
| SCHEMBL8236015 | 0.70 | MAPT (0.43) | ADORA3ADORA2AADORA1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007082666-A1 | ACYLAMINOIMIDAZOLES | BAYER HEALTHCARE AG (DE) | 2007-07-26 | — | — | WO | disclosed |