Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | GRN | P28799 | 2/20 | 0.37 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3494751 | 0.81 | ALDH1A1 (0.52) | ALDH1A1MEN1KMT2APOLBGAA | |
| SCHEMBL3494459 | 0.69 | AOC2 (0.41) | ALDH1A1MEN1KMT2AGAALMNA | |
| SCHEMBL3492508 | 0.67 | F2RL3 (0.61) | ALDH1A1MEN1KMT2APOLBGAA | |
| SCHEMBL7778046 | 0.67 | PTGS2 (0.52) | HTR7HTR1AHTR2A | |
| SCHEMBL7777766 | 0.67 | HTR7 (0.48) | HTR7HTR1AHTR2A | |
| SCHEMBL7778202 | 0.67 | PTGS2 (0.60) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7773087 | 0.66 | PTGS2 (0.48) | KMT2ALMNA | |
| SCHEMBL8890615 | 0.63 | HTT (0.51) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL5441403 | 0.62 | POLB (0.49) | ALDH1A1MEN1KMT2AGRNSORT1 | |
| SCHEMBL4682097 | 0.61 | PTGDR2 (0.51) | PTGER4KCNK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007094513-A2 | CYCLIC AMINE COMPOUND AND USE THEREOF FOR THE PROPHYLAXIS OR TREATMENT OF HYPERTENSION | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-08-23 | — | — | WO | disclosed |