Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 10/20 | 0.44 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.42 |
| ▸ | OGT | O15294 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8233961 | 0.94 | ALDH1A1 (0.56) | ALDH1A1KMT2AKDM4EMEN1HTT | |
| SCHEMBL5320148 | 0.84 | ALDH1A1 (0.54) | ALDH1A1KMT2AKDM4EMEN1HTT | |
| SCHEMBL8236015 | 0.82 | MAPT (0.43) | MAPTSMN1; SMN2GABRA2GABRB2TP53 | |
| SCHEMBL8236523 | 0.79 | OGT (0.45) | ALDH1A1KMT2AKDM4EMEN1HTT | |
| SCHEMBL8227750 | 0.77 | MAPT (0.46) | ALDH1A1KMT2AKDM4EMEN1HTT | |
| SCHEMBL8237709 | 0.74 | MAPT (0.41) | ALDH1A1KMT2AMEN1HTTMAPT | |
| SCHEMBL8235818 | 0.74 | MAPT (0.54) | ALDH1A1KMT2AKDM4EMEN1HTT | |
| SCHEMBL8233022 | 0.72 | ALDH1A1 (0.45) | ALDH1A1KMT2AKDM4EMEN1HTT | |
| SCHEMBL8236412 | 0.71 | SLC6A9 (0.39) | KMT2AMAPTSMN1; SMN2ADORA3ADORA2A | |
| SCHEMBL8236040 | 0.71 | MAPT (0.47) | MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007082666-A1 | ACYLAMINOIMIDAZOLES | BAYER HEALTHCARE AG (DE) | 2007-07-26 | — | — | WO | disclosed |