Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.54 |
| ▸ | LMNA | P02545 | 6/20 | 0.54 |
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | HTT | P42858 | 7/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | MITF | O75030 | 2/20 | 0.51 |
| ▸ | XBP1 | P17861 | 1/20 | 0.51 |
| ▸ | OGT | O15294 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8233961 | 0.91 | ALDH1A1 (0.56) | ALDH1A1LMNAMAPTHTTKDM4E | |
| SCHEMBL8236523 | 0.88 | OGT (0.45) | ALDH1A1LMNAMAPTHTTKDM4E | |
| SCHEMBL8236012 | 0.84 | ALDH1A1 (0.47) | ALDH1A1LMNAMAPTHTTKDM4E | |
| SCHEMBL8233022 | 0.84 | ALDH1A1 (0.45) | ALDH1A1LMNAMAPTHTTKDM4E | |
| SCHEMBL8236014 | 0.83 | MAPT (0.50) | ALDH1A1LMNAMAPTHTTSMN1; SMN2 | |
| SCHEMBL8235818 | 0.83 | MAPT (0.54) | ALDH1A1LMNAMAPTHTTKDM4E | |
| SCHEMBL5342352 | 0.83 | LMNA (0.42) | ALDH1A1LMNAMAPTHTTKDM4E | |
| SCHEMBL8233368 | 0.82 | ALDH1A1 (0.49) | ALDH1A1LMNAMAPTHTTKDM4E | |
| SCHEMBL5338305 | 0.81 | MAPT (0.48) | ALDH1A1LMNAMAPTHTTKDM4E | |
| SCHEMBL28428243 | 0.81 | ADORA3 (0.56) | ALDH1A1LMNAMAPTKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007082666-A1 | ACYLAMINOIMIDAZOLES | BAYER HEALTHCARE AG (DE) | 2007-07-26 | — | — | WO | disclosed |
| WO-2007082666-A1 | ACYLAMINOIMIDAZOLES | BAYER HEALTHCARE AG (DE) | 2007-07-26 | — | — | WO | disclosed |