Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8235817 | 0.86 | OPRM1 (0.32) | DRD2DRD4OPRM1DRD3 | |
| SCHEMBL8236348 | 0.85 | DRD2 (0.35) | DRD2DRD4OPRM1DRD3 | |
| SCHEMBL8238023 | 0.78 | NPY2R (0.33) | — | |
| SCHEMBL2103403 | 0.71 | SIRT2 (0.36) | — | |
| SCHEMBL25464003 | 0.65 | SLC6A4 (0.37) | DRD2 | |
| SCHEMBL2047127 | 0.62 | GABRA1 (0.59) | — | |
| SCHEMBL7135459 | 0.61 | HCRTR2 (0.45) | DRD2 | |
| SCHEMBL13470169 | 0.59 | CYP11B1 (0.33) | — | |
| SCHEMBL14149674 | 0.59 | CYP11B1 (0.31) | — | |
| SCHEMBL422066 | 0.58 | BID (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007085556-A2 | USE OF 4-IMIDAZOLE DERIVATIVES FOR CNS DISORDERS | F. HOFFMANN-LA ROCHE AG (CH) | 2007-08-02 | — | — | WO | disclosed |