Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 8/20 | 0.46 |
| ▸ | SFRP1 | Q8N474 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | IDH2 | P48735 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4393980 | 0.85 | CACNA1B (0.66) | CACNA1BNR1I2CYP3A4 | |
| SCHEMBL8234373 | 0.77 | LMNA (0.49) | CACNA1BSFRP1LMNAIDH2NR1I2 | |
| SCHEMBL4281416 | 0.71 | STS (0.60) | SFRP1DRD2ADRA1DADRA1AADRA1B | |
| SCHEMBL2420848 | 0.71 | CA1 (0.62) | LMNAIDH2DRD2ADRA1DADRA1A | |
| SCHEMBL25146086 | 0.71 | HDAC8 (0.42) | SFRP1IDH2DRD2ADRA1DADRA1A | |
| SCHEMBL25146051 | 0.70 | MGLL (0.45) | SFRP1IDH2DRD2ADRA1DADRA1A | |
| SCHEMBL13880084 | 0.69 | HTR1A (0.52) | LMNAIDH2DRD2ADRA1DADRA1A | |
| SCHEMBL27683100 | 0.68 | HTR1A (0.52) | CACNA1BSFRP1LMNAIDH2DRD2 | |
| SCHEMBL23052376 | 0.68 | HTR1A (0.61) | SFRP1LMNAHTR1AHTR7ALDH1A1 | |
| SCHEMBL8232005 | 0.68 | SFRP1 (0.51) | SFRP1IDH2HTR1AHTR7HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007118854-A1 | BENZENESULFONAMIDE COMPOUNDS AND THE USE THEREOF | EURO-CELTIQUE S.A. (LU) | 2007-10-25 | — | — | WO | disclosed |