SCHEMBL8237403

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8233313	0.81	KDM4E (0.49)	KDM4EALDH1A1NPC1RAB9ATP53
	SCHEMBL18113537	0.78	RAB9A (0.73)	KDM4EALDH1A1NPC1RAB9ATP53
	SCHEMBL930672	0.74	CA2 (0.51)	KDM4EALDH1A1NPC1RAB9AHSD17B10
	SCHEMBL10200978	0.74	KDM4E (0.48)	KDM4EALDH1A1NPC1RAB9ATP53
	SCHEMBL10112910	0.72	KDM4E (0.46)	KDM4EALDH1A1NPC1RAB9ATP53
	SCHEMBL27007846	0.71	CA2 (0.71)	KDM4EALDH1A1NPC1RAB9ATP53
	SCHEMBL8233246	0.71	DGAT1 (0.58)	KDM4ENPC1RAB9AHSD17B10CA2
	SCHEMBL930697	0.71	CA2 (0.48)	KDM4EALDH1A1NPC1RAB9ACA2
	SCHEMBL930734	0.71	CA2 (0.45)	KDM4EALDH1A1NPC1RAB9ATP53
	SCHEMBL11996756	0.67	RAB9A (1.00)	KDM4EALDH1A1NPC1RAB9ATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.