Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13631349 | 0.83 | MAPT (0.38) | KMT2AKDM4EMAPTTDP1MEN1 | |
| SCHEMBL8592870 | 0.80 | KDM4E (0.55) | KMT2AKDM4EMAPTTDP1MEN1 | |
| SCHEMBL19445594 | 0.80 | KDM4E (0.45) | KMT2AKDM4EMAPTTDP1MEN1 | |
| Hydrochloric Acid SCHEMBL7500560 | 0.80 | LMNA (0.40) | KMT2AMAPTMEN1ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL7497463 | 0.80 | ADRA1D (0.47) | KMT2AKDM4EMAPTMEN1ALDH1A1 | |
| SCHEMBL8240087 | 0.76 | MAPT (0.47) | KMT2AMAPTTDP1MEN1THRB | |
| SCHEMBL14418224 | 0.76 | ALOX5 (0.41) | KMT2AKDM4EMAPTTDP1MEN1 | |
| SCHEMBL6999569 | 0.76 | GAA (0.57) | KDM4EMAPTTDP1ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL7497852 | 0.75 | KMT2A (0.49) | KMT2AMAPTTDP1MEN1ALDH1A1 | |
| SCHEMBL11509832 | 0.73 | ALDH1A1 (0.55) | KMT2AKDM4EMAPTTDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007076431-A1 | MACROCYCLIC FACTOR VIIA INHIBITORS USEFUL AS ANTICOAGULANTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-07-05 | — | — | WO | disclosed |