Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR2E1 | Q9Y466 | 3/20 | 0.44 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.43 |
| ▸ | EIF4H | Q15056 | 2/20 | 0.43 |
| ▸ | NCF1 | P14598 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.42 |
| ▸ | RORA | P35398 | 1/20 | 0.41 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16886350 | 0.88 | NSD2 (0.51) | PABPC1EIF4HMEN1KMT2ANSD2 | |
| SCHEMBL27279918 | 0.83 | MAPK1 (0.46) | NR2E1NCF1NSD2PTPN1PTPN11 | |
| SCHEMBL827639 | 0.80 | MEN1 (0.47) | NR2E1NCF1MEN1KMT2ANSD2 | |
| SCHEMBL23193358 | 0.80 | NCF1 (0.50) | NCF1NSD2SLC22A12PTPN1PTPN11 | |
| SCHEMBL28176881 | 0.79 | LMNA (0.45) | NCF1MEN1KMT2ANSD2SLC22A12 | |
| SCHEMBL228713 | 0.78 | KDM4E (0.56) | NCF1MEN1KMT2ANSD2KDM4C | |
| SCHEMBL29375172 | 0.78 | KDM4E (0.56) | NCF1MEN1KMT2ANSD2KDM4C | |
| SCHEMBL23682724 | 0.77 | KDM4E (0.49) | KMT2AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL29381262 | 0.77 | KDM4E (0.57) | NCF1KMT2ANSD2PTPN1PTPN11 | |
| SCHEMBL227218 | 0.77 | NCF1 (0.47) | PABPC1EIF4HNCF1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11731967-B2 | Inhibitors of TRIM33 and methods of use | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2023-08-22 | — | — | US | disclosed |
| US-20090203663-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2009-08-13 | — | — | US | disclosed |
| US-20090137601-A1 | L-Phenylalanine Derivatives | ASTRAZENECA AB (SE) | 2009-05-28 | — | — | US | disclosed |
| US-20090111828-A1 | L-ALANINE DERIVATIVES | ASTRAZENECA AB | 2009-04-30 | — | — | US | disclosed |
| WO-2007060409-A1 | L-ALANINE DERIVATIVES | ASTRAZENECA AB (SE) | 2007-05-31 | — | — | WO | disclosed |
| WO-2007060408-A2 | L-PHENYLALANINE DERIVATIVES AND THEIR USE AS INTEGRIN ANTAGONISTS | ASTRAZENECA AB (SE) | 2007-05-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11731967-B2 | Inhibitors of TRIM33 and methods of use | TRIM33, TRIM28, TRIM4 | NR2E1 1266/4885PABPC1 199/4885EIF4H 1602/4885 |
| US-20090203663-A1 | CHEMICAL COMPOUNDS | ITGB5, ITGB1, ITGA2B | NR2E1 1738/4885PABPC1 1617/4885EIF4H 4464/4885 |
| US-20090111828-A1 | L-ALANINE DERIVATIVES | ITGA2B, ITGB1, ITGB5 | NR2E1 3721/4885PABPC1 539/4885EIF4H 2978/4885 |
| US-20090137601-A1 | L-Phenylalanine Derivatives | ITGB5, ITGB1, ITGA2B | NR2E1 3943/4885PABPC1 250/4885EIF4H 3567/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.