SCHEMBL82420

SCHEMBL82420

[N-]=[N+]=CC(=O)c1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.60
KMT2A Q03164 3/20 0.60
MEN1 O00255 2/20 0.60
HTT P42858 2/20 0.60
HIF1A Q16665 1/20 0.60
MAPK1 P28482 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
CYP1A2 P05177 1/20 0.53
CYP2C9 P11712 1/20 0.53
CYP2C19 P33261 1/20 0.53
AKT1 P31749 1/20 0.52
NPSR1 Q6W5P4 3/20 0.52
NFE2L2 Q16236 1/20 0.50
RECQL P46063 2/20 0.47
PLIN1 O60240 2/20 0.47
LMNA P02545 2/20 0.47
MAPT P10636 2/20 0.47
PLIN5 Q00G26 2/20 0.47
ABHD5 Q8WTS1 2/20 0.47
BCHE P06276 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5585739 0.88 ALDH1A1 (0.58) ALDH1A1KMT2AMEN1HTTHIF1A
SCHEMBL1927123 0.83 KMO (0.55) ALDH1A1KMT2AMEN1HTTHIF1A
SCHEMBL9448941 0.83 ALDH1A1 (0.54) ALDH1A1KMT2AMEN1HTTHIF1A
SCHEMBL9448901 0.79 AKR1C3 (0.60) ALDH1A1CYP1A2CYP2C9CYP2C19LMNA
SCHEMBL9448994 0.78 ALDH1A1 (0.61) ALDH1A1KMT2AMEN1HTTHIF1A
SCHEMBL2073722 0.78 ALDH1A1 (0.61) ALDH1A1KMT2AMEN1HTTHIF1A
SCHEMBL9449020 0.78 ALDH1A1 (0.67) ALDH1A1KMT2AMEN1HTTHIF1A
SCHEMBL9448908 0.78 ALDH1A1 (0.61) ALDH1A1KMT2AMEN1HTTHIF1A
SCHEMBL28605102 0.78 ALDH1A1 (0.61) ALDH1A1KMT2AMEN1HTTHIF1A
SCHEMBL10984695 0.77 NR4A1 (0.62) ALDH1A1KMT2AMEN1HTTHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 662 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117265554-A Method for preparing thioester derivative by electrocatalytic reaction 江苏中利集团股份有限公司 2023-12-22 CN claimed
CN-111925335-B Preparation method of 5-amino-1, 2,3-triazole compound 烟台大学 2021-10-26 CN claimed
CN-111925335-A Preparation method of 5-amino-1, 2,3-triazole compound 烟台大学 2020-11-13 CN claimed
US-20160208114-A1 CONDUCTIVE POLYMERIC COATINGS, MEDICAL DEVICES, COATING SOLUTIONS AND METHODS HERAEUS MEDICAL COMPONENTS LLC 2016-07-21 US claimed
EP-3039087-A1 CONDUCTIVE POLYMERIC COATINGS, MEDICAL DEVICES, COATING SOLUTIONS AND METHODS SurModics, Inc. (US) 2016-07-06 EP claimed
WO-2015031265-A1 CONDUCTIVE POLYMERIC COATINGS, MEDICAL DEVICES, COATING SOLUTIONS AND METHODS SURMODICS, INC. (US) 2015-03-05 WO claimed
US-20030013696-A1 Methods and compositions for photo-cross linking photoactive compounds to target tissue BRITISH COLUMBIA, UNIVERSITY OF, THE (CA) 2003-01-16 US claimed
WO-2002076453-A1 METHODS AND COMPOSITIONS FOR PHOTO-CROSS LINKING PHOTOACTIVE COMPOUNDS TO TARGET TISSUE THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2002-10-03 WO claimed
US-4758312-A Adding colorless electrochemically active compound having positive reduction potential NALCO CHEMICAL COMPANY (US) 1988-07-19 US claimed
US-3976621-A ALPHA-DIAZOACETOPHENONES, LEWIS ACID CATALYST SNAM PROGETTI S.P.A. (IT) 1976-08-24 US claimed
US-12616777-B2 Silicone polyurea block copolymer coating compositions and methods INNOVATIVE SURFACE TECHNOLOGIES, INC. (US) 2026-05-05 US disclosed
US-20260108663-A1 LOW PARTICULATE LUBRICIOUS COATING WITH VINYL PYRROLIDONE AND ACIDIC POLYMER-CONTAINING LAYERS SURMODICS INC (US) 2026-04-23 US disclosed
US-12582752-B2 Medical device and method for manufacturing same TERUMO KABUSHIKI KAISHA (JP) 2026-03-24 US disclosed
EP-3723820-B1 SILICONE POLYUREA BLOCK COPOLYMER COATING COMPOSITIONS AND METHODS INNOVATIVE SURFACE TECH INC (US) 2026-02-11 EP disclosed
US-12409253-B2 Low particulate lubricious coating with vinyl pyrrolidone and acidic polymer-containing layers SURMODICS, INC. (US) 2025-09-09 US disclosed
US-4268442-A REACTING AN AROMATIC ALKEHYDE WITH A TRIHALOMETHANE AND AN ALKANETHIOL IN THE PRESENCE OF A BASE AND AN APROTIC SOLVENT SAGAMI CHEMICAL RESEARCH CENTER (JP) 1981-05-19 US disclosed
EP-0025496-A1 Maytansinoids, their production and therapeutic compositions containing them Takeda Chemical Industries, Ltd. (JP) 1981-03-25 EP disclosed
US-4228174-A ANTIBIOTICS BEECHAM GROUP LIMITED (GB) 1980-10-14 US disclosed
US-3976621-A ALPHA-DIAZOACETOPHENONES, LEWIS ACID CATALYST SNAM PROGETTI S.P.A. (IT) 1976-08-24 US disclosed
US-3976621-A ALPHA-DIAZOACETOPHENONES, LEWIS ACID CATALYST SNAM PROGETTI S.P.A. (IT) 1976-08-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12582752-B2 Medical device and method for manufacturing same STS, DEGS1, HPSE ALDH1A1 790/4885KMT2A 3204/4885MEN1 2136/4885
US-12616777-B2 Silicone polyurea block copolymer coating compositions and methods PGF, CASK, C9 ALDH1A1 3120/4885KMT2A 1577/4885MEN1 2659/4885
US-20260108663-A1 LOW PARTICULATE LUBRICIOUS COATING WITH VINYL PYRROLIDONE AND ACIDIC POLYMER-CONTAINING LAYERS VCL, RAD54L, SELP ALDH1A1 751/4885KMT2A 808/4885MEN1 2678/4885
US-20030013696-A1 Methods and compositions for photo-cross linking photoactive compounds to target tissue LCP1, PPOX, TYR ALDH1A1 542/4885KMT2A 3404/4885MEN1 4224/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.