Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 12/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20478656 | 0.81 | DRD4 (0.50) | DRD4HTR1A | |
| SCHEMBL266635 | 0.77 | DRD2 (0.50) | DRD2DRD3HTR1A | |
| SCHEMBL15577014 | 0.75 | DRD2 (0.49) | DRD2DRD3HTR1A | |
| SCHEMBL7214403 | 0.75 | PIN1 (0.52) | DRD2HTR1A | |
| SCHEMBL265887 | 0.73 | ACHE (0.58) | DRD2DRD3HTR1A | |
| SCHEMBL598626 | 0.73 | ACHE (0.58) | DRD2DRD3HTR1A | |
| SCHEMBL17014302 | 0.73 | HTR1A (0.50) | DRD2DRD3HTR1A | |
| SCHEMBL30563633 | 0.73 | ACHE (0.58) | DRD2DRD3HTR1A | |
| SCHEMBL26962405 | 0.73 | ACHE (0.58) | DRD2DRD3HTR1A | |
| Hydrochloric Acid SCHEMBL659578 | 0.72 | ACHE (0.61) | DRD2DRD3HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007085558-A1 | USE OF 2-IMIDAZOLES FOR THE TREATMENT OF CNS DISORDERS | F. HOFFMANN-LA ROCHE AG (CH) | 2007-08-02 | — | — | WO | disclosed |