SCHEMBL824394

SCHEMBL824394

c1cc2c3c(cccc3c1)-c1nc3ccccc3nc1-2

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.58
ALDH1A1 P00352 7/20 0.56
HSD17B10 Q99714 4/20 0.56
TSHR P16473 3/20 0.56
MAPK1 P28482 3/20 0.56
L3MBTL1 Q9Y468 2/20 0.56
ATM Q13315 1/20 0.56
MAPT P10636 4/20 0.54
SMN1; SMN2 Q16637 3/20 0.54
NPC1 O15118 3/20 0.54
RAB9A P51151 3/20 0.54
AHR P35869 1/20 0.54
TP53 P04637 3/20 0.50
CASP1 P29466 2/20 0.50
CASP7 P55210 2/20 0.50
HPGD P15428 1/20 0.50
HIF1A Q16665 1/20 0.50
CES2 O00748 1/20 0.46
BCHE P06276 1/20 0.46
CES1 P23141 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31187046 1.00 CYP1A2 (0.58) CYP1A2ALDH1A1HSD17B10TSHRMAPK1
SCHEMBL29867529 0.86 ALDH1A1 (0.58) CYP1A2ALDH1A1HSD17B10TSHRMAPK1
SCHEMBL903607 0.86 ALDH1A1 (0.58) CYP1A2ALDH1A1HSD17B10TSHRMAPK1
SCHEMBL12874082 0.86 CYP1A2 (0.59) CYP1A2ALDH1A1HSD17B10TSHRMAPK1
SCHEMBL2489961 0.82 MAPT (0.73) CYP1A2ALDH1A1HSD17B10TSHRMAPK1
SCHEMBL824409 0.81 CYP1A2 (0.59) CYP1A2ALDH1A1HSD17B10TSHRMAPK1
SCHEMBL14541683 0.81 RAB9A (0.58) CYP1A2ALDH1A1HSD17B10TSHRMAPK1
SCHEMBL13319594 0.81 CYP1A2 (0.46) CYP1A2ALDH1A1HSD17B10TSHRMAPK1
SCHEMBL12902796 0.80 ALDH1A1 (0.46) CYP1A2ALDH1A1HSD17B10TSHRMAPK1
SCHEMBL824424 0.80 CYP1A2 (0.46) CYP1A2ALDH1A1HSD17B10TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 211 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8253899-B2 Birefringent film NITTO DENKO CORPORATION (JP) 2012-08-28 US claimed
JP-4798802-B2 2011-10-19 JP claimed
EP-1853948-B1 COMPENSATOR FOR LIQUID CRYSTAL DISPLAY NITTO DENKO CORP (JP) 2011-10-05 EP claimed
US-7736707-B2 Birefringent film, polycyclic compound, coating liquid, and image display device NITTO DENKO CORPORATION (JP) 2010-06-15 US claimed
US-7733443-B2 LCD comprising backlight and reflective polarizer on front panel NITTO DENKO CORPORATION (JP) 2010-06-08 US claimed
US-20100128211-A1 BIREFRINGENT FILM, LAMINATED FILM, AND IMAGE DISPLAY DEVICE NITTO DENKO CORPORATION (JP) 2010-05-27 US claimed
US-20100047483-A1 BIREFRINGENT FILM, LAMINATED FILM, AND IMAGE DISPLAY DEVICE NITTO DENKO CORPORATION (JP) 2010-02-25 US claimed
US-20090262297-A1 PRODUCTION METHOD FOR BIREFRINGENT FILM, BIREFRINGENT FILM, AND LAMINATE NITTO DENKO CORPORATION (JP) 2009-10-22 US claimed
US-20090197065-A1 BIREFRINGENT FILM, PRODUCTION METHOD THEREOF AND USE THEREOF NITTO DENKO CORPORATION (JP) 2009-08-06 US claimed
US-7527834-B2 Retardation films for the elimination of leakage of light through cross polarizers in LCD NITTO DENKO CORPORATION (JP) 2009-05-05 US claimed
US-20060292372-A1 Retardation films for the elimination of leakage of light through cross polarizers in LCD NITTO DENKO CORPORATION 2006-12-28 US claimed
WO-2006092875-A1 COMPENSATOR FOR LIQUID CRYSTAL DISPLAY NITTO DENKO CORPORATION (JP) 2006-09-08 WO claimed
EP-1663995-A1 SULFODERIVATIVES OF ACENAPHTHO [1,2-B]QUINOXALINE, LYOTROPIC LIQUID CRYSTAL AND ANISOTROPIC FILM ON THEIR BASE NITTO DENKO CORPORATION (JP) 2006-06-07 EP claimed
US-7045177-B2 Concurrent applying, molecular orientation; dissolving in solvent; applying to substrate; drying NITTO DENKO CORPORATION (JP) 2006-05-16 US claimed
WO-2006038404-A1 LCD COMPRISING BACKLIGHT AND REFLECTIVE POLARIZER ON FRONT PANEL NITTO DENKO CORPORATION (JP) 2006-04-13 WO claimed
WO-2006025474-A1 RETARDATION FILMS FOR THE ELIMINATION OF LEAKAGE OF LIGHT THROUGH CROSS POLARIZERS IN LCD NITTO DENKO CORPORATION (JP) 2006-03-09 WO claimed
US-20050200771-A1 LCD comprising backlight and reflective polarizer on front panel INSOLVENCY SERVICES GROUP, INC. 2005-09-15 US claimed
US-20050196550-A1 Compensator for liquid crystal display INSOLVENCY SERVICES GROUP, INC. 2005-09-08 US claimed
WO-2005051926-A1 SULFODERIVATIVES OF ACENAPHTHO[1,2-B]QUINOXALINE, LYOTROPIC LIQUID CRYSTAL AND ANISOTROPIC FILM ON THEIR BASE NITTO DENKO CORPORATION (JP) 2005-06-09 WO claimed
US-20050109986-A1 Concurrent applying, molecular orientation; dissolving in solvent; applying to substrate; drying INSOLVENCY SERVICES GROUP, INC. 2005-05-26 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090197065-A1 BIREFRINGENT FILM, PRODUCTION METHOD THEREOF AND USE THEREOF C5, NQO2, C1QBP CYP1A2 1007/4885ALDH1A1 3294/4885HSD17B10 2684/4885
US-20050109986-A1 Concurrent applying, molecular orientation; dissolving in solvent; applying to substrate; drying CFH, CCNH, HCN3 CYP1A2 1504/4885ALDH1A1 3399/4885HSD17B10 1543/4885
US-20100047483-A1 BIREFRINGENT FILM, LAMINATED FILM, AND IMAGE DISPLAY DEVICE CFH, C1R, AQP3 CYP1A2 1179/4885ALDH1A1 3558/4885HSD17B10 3424/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.