Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.69 |
| ▸ | TNF | P01375 | 2/20 | 0.69 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.69 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.69 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | DRD2 | P14416 | 1/20 | 0.59 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | CFTR | P13569 | 1/20 | 0.49 |
| ▸ | CSF1R | P07333 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7165480 | 0.88 | TNF (0.87) | NOD1TNFNOD2CXCL8SOS1 | |
| SCHEMBL17819068 | 0.85 | KMT2A (0.59) | NOD1TNFNOD2CXCL8SOS1 | |
| SCHEMBL8483250 | 0.85 | CYP11B1 (0.55) | NOD1TNFNOD2CXCL8SOS1 | |
| SCHEMBL4092820 | 0.84 | DRD2 (0.64) | NOD1TNFNOD2CXCL8SOS1 | |
| SCHEMBL939417 | 0.83 | TNF (0.79) | NOD1TNFNOD2CXCL8SOS1 | |
| SCHEMBL7530572 | 0.82 | TNF (0.72) | NOD1TNFNOD2CXCL8SOS1 | |
| SCHEMBL7337702 | 0.82 | NOD1 (1.00) | NOD1TNFNOD2CXCL8SOS1 | |
| SCHEMBL9630558 | 0.81 | TNF (0.75) | NOD1TNFNOD2CXCL8SOS1 | |
| Hydrochloric Acid SCHEMBL11594488 | 0.79 | TNF (0.73) | NOD1TNFNOD2CXCL8SOS1 | |
| SCHEMBL5462900 | 0.79 | POLB (0.50) | NOD1TNFNOD2CXCL8SOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7956196-B2 | the major cause of lower respiratory tract illness during infancy and childhood | TIBOTEC PHARMACEUTICALS LTD. (IE) | 2011-06-07 | — | — | US | disclosed |
| US-20080146564-A1 | 1,3-Dihydro-Benzimidazol-2-Ylidene Amines as Inhibitors of Respiratory Syncytial Virus Replication | JANSSEN SCIENCES IRELAND UC (IE) | 2008-06-19 | — | — | US | disclosed |
| WO-2006097534-A1 | 1,3-DIHYDRO-BENZIMIDAZOL-2-YLIDENE AMINES AS INHIBITORS OF RESPIRATORY SYNCYTIAL VIRUS REPLICATION | TIBOTEC PHARMACEUTICALS LTD (IE) | 2006-09-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080146564-A1 | 1,3-Dihydro-Benzimidazol-2-Ylidene Amines as Inhibitors of Respiratory Syncytial Virus Replication | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CBR1, RTF2 | NOD1 241/4885TNF 4684/4885NOD2 2023/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.