Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A7 | Q99884 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.46 |
| ▸ | GPR6 | P46095 | 3/20 | 0.45 |
| ▸ | USP2 | O75604 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MLYCD | O95822 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | PHGDH | O43175 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8247829 | 0.87 | USP2 (0.53) | SLC6A7ALDH1A1KDM4EL3MBTL1MEN1 | |
| SCHEMBL4722342 | 0.81 | MEN1 (0.71) | ALDH1A1KDM4EL3MBTL1MEN1KMT2A | |
| SCHEMBL8246614 | 0.81 | ALDH1A1 (0.62) | ALDH1A1KMT2AHTTTSHRSMN1; SMN2 | |
| SCHEMBL1870288 | 0.81 | SLC6A7 (0.52) | SLC6A7MEN1KMT2AMAPK1HTT | |
| SCHEMBL4718989 | 0.79 | ALDH1A1 (0.53) | ALDH1A1KDM4EL3MBTL1MEN1KMT2A | |
| SCHEMBL8247070 | 0.78 | SMN1; SMN2 (0.72) | SLC6A7ALDH1A1KDM4EL3MBTL1MEN1 | |
| SCHEMBL4763376 | 0.78 | SLC6A7 (0.48) | SLC6A7ALDH1A1MEN1KMT2AGPR6 | |
| SCHEMBL4719103 | 0.78 | ABL1 (0.55) | ALDH1A1KDM4EL3MBTL1MAPK1HTT | |
| SCHEMBL4722869 | 0.76 | AKR1C3 (0.58) | ALDH1A1KDM4EL3MBTL1MEN1KMT2A | |
| SCHEMBL4766135 | 0.76 | USP2 (0.57) | SLC6A7ALDH1A1KDM4EL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007009635-A1 | PHENYL SUBSTITUTED PIPERAZINE-DERIVATIVES AS INHIBITORS OF PLAMINOGENIC ACTIVATOR INHIBITORS-I (PAI-I) | BAYER HEALTHCARE AG (DE) | 2007-01-25 | — | — | WO | disclosed |