Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 10/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | PKLR | P30613 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL67448 | 0.83 | ALDH1A1 (0.52) | CA12CA1CA2CA9NFE2L2 | |
| SCHEMBL775608 | 0.78 | HTR2C (0.59) | CA12CA1CA2CA9NFE2L2 | |
| SCHEMBL851628 | 0.77 | CES2 (0.46) | CA12CA1CA2CA9NFE2L2 | |
| SCHEMBL7534260 | 0.76 | HTR2A (0.50) | CA12CA1CA2CA9NFE2L2 | |
| SCHEMBL15514618 | 0.76 | CA12 (0.47) | CA12CA1CA2CA9NFE2L2 | |
| SCHEMBL1889098 | 0.76 | CA12 (0.47) | CA12CA1CA2CA9NFE2L2 | |
| SCHEMBL2045020 | 0.74 | TSHR (0.57) | CA12CA1CA2CA9NFE2L2 | |
| SCHEMBL775429 | 0.74 | PTGS2 (0.47) | CA12CA1CA2CA9NFE2L2 | |
| SCHEMBL1137782 | 0.74 | CA2 (0.70) | CA12CA1CA2CA9 | |
| SCHEMBL1299098 | 0.74 | CA12 (0.46) | CA12CA1CA2CA9NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006116157-A9 | DIPEPTIDYL PEPTIDASE-IV INHIBITORS | ALANTOS PHARMACEUTICALS INC (US) | 2007-03-01 | — | — | WO | disclosed |
| WO-2006116157-A2 | DIPEPTIDYL PEPTIDASE-IV INHIBITORS | ALANTOS PHARMACEUTICALS HOLDING, INC. (US) | 2006-11-02 | — | — | WO | disclosed |