SCHEMBL825377

SCHEMBL825377

CCC(C)(C)c1cccc(O)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44
MAPK1 P28482 1/20 0.44
CASP3 P42574 1/20 0.44
ATM Q13315 1/20 0.44
SENP8 Q96LD8 1/20 0.44
SENP7 Q9BQF6 1/20 0.44
SENP6 Q9GZR1 1/20 0.44
ALDH1A1 P00352 2/20 0.44
CYP3A4 P08684 2/20 0.44
CA12 O43570 1/20 0.44
CA2 P00918 1/20 0.44
CA5A P35218 1/20 0.44
CA9 Q16790 1/20 0.44
HSD17B10 Q99714 1/20 0.44
CA14 Q9ULX7 1/20 0.44
CA5B Q9Y2D0 1/20 0.44
ESR1 P03372 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31215161 1.00 LMNA (0.44) LMNASMN1; SMN2NPC1RAB9AMAPK1
Phenol SCHEMBL28873361 0.88 ESR1 (0.50) LMNASMN1; SMN2NPC1RAB9AMAPK1
SCHEMBL779789 0.84 MAPK1 (0.52) LMNASMN1; SMN2NPC1RAB9AMAPK1
SCHEMBL5648833 0.84 CNR1 (0.43) LMNAALDH1A1CYP3A4CA12CA2
SCHEMBL13930904 0.83 ESR1 (0.44) LMNASMN1; SMN2ALDH1A1CYP3A4CA12
SCHEMBL11783483 0.83 ALDH1A1 (0.44) LMNASMN1; SMN2ALDH1A1CYP3A4CA12
SCHEMBL6027444 0.83 CNR1 (0.46) LMNAALDH1A1CYP3A4CA12CA2
SCHEMBL393199 0.83 ESR1 (0.58) LMNASMN1; SMN2ALDH1A1CYP3A4CA12
Water SCHEMBL27961448 0.82 MAPK1 (0.50) LMNASMN1; SMN2NPC1RAB9AMAPK1
Phenol SCHEMBL11800897 0.82 HSD17B1 (0.44) LMNASMN1; SMN2NPC1RAB9AMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 283 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240219830-A1 SALT, ACID GENERATOR, RESIST COMPOSITION AND METHOD FOR PRODUCING RESIST PATTERN SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2024-07-04 US disclosed
CN-110003582-B Heat-resistant styrene resin composition, molded article, extruded sheet, and container for food packaging 东洋苯乙烯股份有限公司 2024-07-02 CN disclosed
US-20240210824-A1 CARBOXYLATE, CARBOXYLIC ACID GENERATOR, RESIST COMPOSITION AND METHOD FOR PRODUCING RESIST PATTERN SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2024-06-27 US disclosed
CN-114599688-B Method for preparing vinyl chloride polymer composite material, vinyl chloride polymer composite material and composition comprising the same 株式会社LG化学 2024-02-06 CN disclosed
US-11840503-B2 Salt, acid generator, resist composition and method for producing resist pattern SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-12-12 US disclosed
US-20230384676-A1 RADIATION-SENSITIVE RESIN COMPOSITION, METHOD OF FORMING PATTERN, POLYMER, AND COMPOUND JSR CORPORATION (JP) 2023-11-30 US disclosed
US-11822244-B2 Compound, resin, resist composition and method for producing resist pattern SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-11-21 US disclosed
US-11822241-B2 Salt, acid generator, resist composition and method for producing resist pattern SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-11-21 US disclosed
US-11822244-B2 Compound, resin, resist composition and method for producing resist pattern SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-11-21 US disclosed
US-11820736-B2 Salt, acid generator, resist composition and method for producing resist pattern SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-11-21 US disclosed
EP-0252007-A2 2-Propanol derivatives as corrosion inhibitors CIBA-GEIGY AG (CH) 1988-01-07 EP disclosed
US-4692555-A Preparation of diphenolics ETHYL CORPORATION (US) 1987-09-08 US disclosed
EP-0032062-B1 HIGH-MOLECULAR-WEIGHT NOVOLAK SUBSTITUTED PHENOLIC RESINS AND THEIR PREPARATION MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1985-04-03 EP disclosed
EP-0032060-B1 NOVOLAK RESIN COMPOSITION AND PRODUCTS FORMED THEREFROM MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1984-10-24 EP disclosed
US-4391827-A 3-(2-Hydroxy-4-(substituted)phenyl)-cycloalkanone and cycloalkanol analgesic agents and intermediates therefor PFIZER INC. (US) 1983-07-05 US disclosed
US-4345054-A High-molecular-weight novolak types substituted phenolic resins and process for preparation thereof MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1982-08-17 US disclosed
US-4342852-A Setting type resin composition containing a substantially linear, high-molecular-weight novolak substituted phenolic resin MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1982-08-03 US disclosed
US-4306097-A 3-[2-Hydroxy-4-(substituted)phenyl]-cycloalkanol analgesic agents PFIZER INC. (US) 1981-12-15 US disclosed
EP-0032062-A2 High-molecular-weight novolak substituted phenolic resins and their preparation MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1981-07-15 EP disclosed
EP-0032060-A2 Novolak resin composition and products formed therefrom MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1981-07-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240210824-A1 CARBOXYLATE, CARBOXYLIC ACID GENERATOR, RESIST COMPOSITION AND METHOD FOR PRODUCING RESIST PATTERN SCO2, CBR1, OXGR1 LMNA 4690/4885SMN1; SMN2 4386/4885NPC1 4049/4885
US-20230384676-A1 RADIATION-SENSITIVE RESIN COMPOSITION, METHOD OF FORMING PATTERN, POLYMER, AND COMPOUND RER1, RFT1, RAD51 LMNA 1058/4885SMN1; SMN2 2998/4885NPC1 3033/4885
US-11822244-B2 Compound, resin, resist composition and method for producing resist pattern RER1, AFF1, AFF4 LMNA 3320/4885SMN1; SMN2 1754/4885NPC1 2284/4885
US-20240219830-A1 SALT, ACID GENERATOR, RESIST COMPOSITION AND METHOD FOR PRODUCING RESIST PATTERN H1-0, HCN3, RER1 LMNA 3803/4885SMN1; SMN2 4431/4885NPC1 2198/4885
US-11820736-B2 Salt, acid generator, resist composition and method for producing resist pattern H1-10, H1-0, H1-2 LMNA 4023/4885SMN1; SMN2 3424/4885NPC1 3894/4885
US-11822241-B2 Salt, acid generator, resist composition and method for producing resist pattern H1-10, H1-0, CHRM1 LMNA 3440/4885SMN1; SMN2 1965/4885NPC1 3982/4885
US-11840503-B2 Salt, acid generator, resist composition and method for producing resist pattern RER1, H1-0, CA7 LMNA 4757/4885SMN1; SMN2 3407/4885NPC1 3378/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.