Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 13/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.54 |
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14865143 | 0.87 | OPRD1 (0.52) | OPRD1OPRM1OPRK1DPP4 | |
| SCHEMBL8255087 | 0.84 | DPP4 (0.37) | OPRD1OPRM1OPRK1DPP4 | |
| SCHEMBL16327947 | 0.77 | DPP4 (0.68) | DPP4 | |
| SCHEMBL29351429 | 0.77 | ACE (0.59) | DPP4 | |
| SCHEMBL11059764 | 0.77 | OPRD1 (0.68) | OPRD1OPRM1OPRK1 | |
| SCHEMBL11065582 | 0.76 | OPRD1 (0.67) | OPRD1OPRM1OPRK1 | |
| SCHEMBL9724057 | 0.76 | OPRD1 (0.70) | OPRD1OPRM1OPRK1 | |
| SCHEMBL8673006 | 0.76 | OPRD1 (0.70) | OPRD1OPRM1OPRK1 | |
| SCHEMBL8673162 | 0.76 | OPRD1 (0.70) | OPRD1OPRM1OPRK1 | |
| SCHEMBL29839269 | 0.75 | SLC6A2 (0.55) | OPRM1DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2526942-B1 | Methods of facilitating neural cell survival using non-peptide and peptide BDNF neurotrophin mimetics | UNIV NORTH CAROLINA CHAPEL HILL (US) | 2017-08-09 | — | — | EP | disclosed |
| WO-2006133353-A2 | METHODS OF FACILITATING NEURAL CELL SURVIVAL USING NON-PEPTIDE AND PEPTIDE BDNF NEUROTROPHIN MIMETICS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2006-12-14 | — | — | WO | disclosed |