Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | PREP | P48147 | 1/20 | 0.37 |
| ▸ | FAP | Q12884 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 11/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | CALCRL | Q16602 | 2/20 | 0.34 |
| ▸ | RAMP1 | O60894 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8253792 | 0.84 | OPRD1 (0.54) | DPP4OPRD1OPRM1OPRK1 | |
| SCHEMBL14865143 | 0.71 | OPRD1 (0.52) | DPP4OPRD1OPRM1OPRK1 | |
| SCHEMBL30485831 | 0.69 | ACE (0.43) | DPP4PREPFAP | |
| SCHEMBL29666810 | 0.66 | ACE (0.43) | DPP4PREPFAP | |
| SCHEMBL2557248 | 0.66 | DPP4 (0.61) | DPP4PREPFAP | |
| SCHEMBL2557245 | 0.66 | DPP4 (0.61) | DPP4PREPFAP | |
| SCHEMBL13437289 | 0.66 | FAP (0.44) | DPP4PREPFAP | |
| SCHEMBL8251925 | 0.65 | DPP4 (0.44) | DPP4PREPFAP | |
| SCHEMBL31411888 | 0.65 | ACE (0.55) | CALCRLRAMP1 | |
| SCHEMBL29591172 | 0.64 | PREP (0.44) | DPP4PREPFAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006133353-A2 | METHODS OF FACILITATING NEURAL CELL SURVIVAL USING NON-PEPTIDE AND PEPTIDE BDNF NEUROTROPHIN MIMETICS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2006-12-14 | — | — | WO | disclosed |